Browsing by Subject "Biophysics"
Now showing items 1-7 of 7
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Elucidating the Mechanism of Action of Unnatural Amino Acid Containing Antimicrobial Peptides in Membrane Environments
(East Carolina University, 2012)Organism resistance continues to develop to the currently available antimicrobial compounds necessitating the development of innovative new therapeutic compounds with different specificities and mechanisms of action that ... -
Mathematical Modeling of Oxygen Transport, Cell Killing and Cell Decision Making in Photodynamic Therapy of Cancer
(East Carolina University, 2012)In this study we present a model of in vitro cell killing through type II Photodynamic Therapy (PDT) for simulation of the molecular interactions leading to cell death in time domain in the presence of oxygen transport ... -
Photofrin-Mediated Electroporation-Assisted Photodynamic Therapy of MCF-7 Human Breast Cancer and B16-F10 Mouse Melanoma Cells
(East Carolina University, 2011)Photodynamic therapy is a relatively new player on the field of cancer treatment that involves the injection of a nontoxic light-sensitive drug followed by light excitation, creating reactive oxygen species that cause ... -
A PROPOSED METHODOLOGY TO ASSESS HDR [superscript]192Ir RADIAL DOSE WITH FRICKE DOSIMETRY
(East Carolina University, 2011)The radial absorbed dose to water, D(r,theta), a quantity not yet directly measured with primary standards, was assessed with the Fricke solution which has been considered as an absolute aqueous solution to perform dosimetry. ... -
Secondary Electron Emission Yields from Fast Fluorine Ions on Copper and Amorphous Solid Water Foils
(East Carolina University, 2011)The biological outcomes from charged particle radiation exposure are heavily influenced by the spatial patterns of energy distributed within the biological system. Monte Carlo track structure codes can be used to model ... -
Study of Morphology Based Cell Assay by Diffraction Imaging Flow Cytometry
(East Carolina University, 2015)Development of an accurate and label-free method for single cell assay attracts intensive research efforts for its importance to cell biology research and clinicG14G7al applications. Flow cytometry is one of the most widely ... -
VIABILITY OF CERIUM OXIDE NANOPARTICLES AS A RADIOPROTECTOR AGAINST PROTON RADIATION FOR NON-MALIGNANT CELLS
(East Carolina University, 2015)Radiation therapy is a prevalent cancer treatment therapy. The goal is to kill all tumor cells while minimizing damage to healthy cells and new methods that can accomplish this goal are continually being investigated. ...