Browsing by Subject "Calcium"
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Optical and dielectric properties of metallic calcium, modeled generalized oscillator strength function of calcium, interaction cross sections of electrons, protons, and alpha particles with calcium
(East Carolina University, 2013)An analysis of the optical and the dielectric properties of calcium, determined from the literature, was performed. The optical functions of calcium were used for a calculation of the energy loss function of calcium. The ... -
The Physiological and Pathological Role of Mitochondrial Calcium in the Diabetic Heart
(East Carolina University, 2011)Diabetic patients are more susceptible to ischemia/reperfusion injury and cardiac dysfunction likely due alterations in mitochondrial calcium handling. The purpose of this work was to determine if redox-dependent changes ... -
The C-terminus of Troponin T Modulates Calcium Regulation of Actin-Myosin Interactions
(East Carolina University, 2019-05-02)The highly conserved terminal fourteen C-terminal residues of troponin T play a novel role in the regulation of striated muscle contraction. Elimination of the terminal fourteen residues of the C-terminal region of troponin ... -
The Thermodynamics of Cd(II) Binding to Human Cardiac Troponin C: Using Mutants to Determine the Location of Cd(II) Binding
(East Carolina University, 2017-05-31)Historically, cadmium (Cd) has been used in many different applications from cadmium paint to nickel-cadmium batteries. However, Cd is a nonessential, naturally occurring toxic element due to its low excretion rate and ... -
Thermodynamic studies of Ca²⁺ binding to human cardiac troponin C
(East Carolina University, 2012)Human Cardiac Troponin C (HcTnC) is an EF hand protein responsible for initiating contraction of the myocardium (heart muscle). The helix-loop-helix motif, characteristic of members of the EF-hand family, allows HcTnC to ...