Browsing by Subject "Cancer--Research"
Now showing items 1-2 of 2
-
Developing Novel Chemotherapeutics: A Structure-Activity Study of Anandamide Analogs and their Cytotoxic Profiles
(East Carolina University, 2020-01-06)Many epithelial cancers have been shown to overexpress the enzyme cyclooxygenase-2 (COX-2), an enzyme responsible for both the metabolism of arachidonic acid (AA) to prostaglandins and arachidonoyl ethanolamine (AEA) to ... -
DIFFERENTIATION OF J-SERIES PROSTAGLANDINS AS PRO-APOPTOTIC PRODUCTS OF CANCER CELL METABOLISM
(East Carolina University, 2016-12-16)Cyclopentenone J-series prostaglandins and prostaglandin-ethanolamide conjugates have been shown to selectively induce endoplasmic reticulum stress-apoptosis in different cancer cell types. These lipids have been identified ...