Browsing by Subject "Cartilage, Articular"
Now showing items 1-2 of 2
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A QUEST FOR ARTICULAR CARTILAGE PROGENITOR CELLS LEADS TO TEMPORAL REGULATION OF HYALURONAN REQUIRED FOR 3T3-L1 ADIPOGENESIS
(East Carolina University, 2017-07-13)During embryogenesis, mesenchymal progenitor cells exhibit hyaluronan-dependent pericellular matrices as a major component of the extracellular matrix. As connective tissues form by cellular condensations, there is a loss ... -
CRISPR/Cas9 knockout of HAS2 in rat chondrosarcoma chondrocytes demonstrates the requirement of hyaluronan for aggrecan retention
(East Carolina University, 2016-12-15)Hyaluronan (HA) plays an essential role in cartilage where it functions to retain aggrecan. Previous studies suggested that aggrecan is anchored indirectly to the plasma membrane of chondrocytes via its binding to ...