Browsing by Subject "Glycosylation"
Now showing items 1-3 of 3
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Effects Of Extracellular Matrix Stiffness On Muscle Fiber Mechanotransduction Signaling In Aged Rats
(East Carolina University, 2015)The loss of muscle mass with age, termed sarcopenia, is a common problem among the over 60 years-old population. Resistance training is often prescribed as treatment, but older adults have shown a reduced response to ... -
Impaired N-Glycosylation Processing Impacts Neuronal Function
(East Carolina University, 2021-07-29)Modifications of membrane proteins are carried out primarily using N-linked glycosylation. N-glycosylation has the potential to co-translationally and post-translationally modify protein function by the addition and ... -
THE IMPACT OF GLYCOSYLATION ON ACTIVE SITE STRUCTURE AND ACTIVITY IN THE FUNGUS ENZYME MOLOX
(East Carolina University, 2019-05-01)Lipoxygenases from pathogenic fungi belong to the lipoxygenase family that catalyze the C-H activation of polyunsaturated fatty acids to form diverse hydroperoxides. While the lipoxygenase catalytic domains are structurally ...