Browsing by Subject "Mitochondrial pathology"
Now showing items 1-3 of 3
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AMP Deaminase 3 knockout mice and loss of mitochondrial proteins and enzyme activity during denervation atrophy
(East Carolina University, 2018-07-17)Muscle atrophy leads to decrements in muscle function, partly attributable to decreased mitochondrial content. One controller of mitochondrial content is AMP-activated protein kinase (AMPK), which when bound by AMP activates ... -
Effect of Acute Exercise or Fasting on Mitochondrial Function and High Fat Diet-Induced Insulin Resistance
(East Carolina University, 2009)A high-fat diet leads to an accumulation of lipid in skeletal muscle, and the development of both mitochondrial dysfunction and insulin resistance. Recently, our lab reported that lipid overload leads to elevated ... -
The effects of statins on mitochondrial function
(East Carolina University, 2013)Statins, or 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, are among the most commonly prescribed medications in the United States. They are commonly used to treat hypercholesterolemia, a condition ...