Browsing by Subject "Morphine"
Now showing items 1-2 of 2
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CENTRAL SENSORIMOTOR CHANGES DUE TO PERIPHERAL NERVE INJURY: ROLE OF DOPAMINERGICS AND OPIOIDS
(East Carolina University, 2022-04-28)Chronic neuropathic pain (CNP) is a disease typically resulting from injury to the central or peripheral nervous system. CNP has a prevalence of 12-15% in the population, but current treatments are not highly efficacious ... -
Identification of Factors Associated with the Development and Decay of Heterologous Tolerance to Morphine in the Guinea Pig
(East Carolina University, 2016-05-03)It is believed that the heterologous tolerance that develops upon chronic exposure to morphine is the result of adaptive changes in the cellular signaling pathways associated with the [mu] opioid receptor. Proposed adaptive ...