Browsing by Subject "Muscle, Skeletal"
Now showing items 1-3 of 3
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Determining the role of BRCA1 in skeletal muscle regeneration
(East Carolina University, 2022-07-15)Skeletal muscle is necessary for movement, breathing, and performance of daily activities. Acute injuries can occur to skeletal muscle, and there are several conditions and diseases that result in impairment of muscle ... -
Induced ablation of skeletal muscle-specific estrogen receptor-alpha in adult female mice increased the susceptibility to develop skeletal muscle inflammation and glucose intolerance under chronic lipid overload
(East Carolina University, 2018-04-27)Skeletal muscle-specific ER[alpha] appears to play important roles in regulating skeletal muscle glucose and lipid homeostasis. The overall aim of this dissertation was to determine whether skeletal muscle-specific ER[alpha] ... -
Physiologic Determinants of Ischemic Skeletal Muscle Pathophysiology
(East Carolina University, 2018-11-29)Lower limb peripheral arterial occlusive disease (PAD) has major impacts on patient quality of life and, in its most severe form, carries a significant risk of mortality. The canonical approach to PAD research has been ...