Browsing by Subject "Matricryptin"

Now showing items 1-2 of 2

  • Collagen matricryptin promotes cardiac function by mediating scar formation 

    Grilo, Gabriel A.; Cakir, Sirin N.; Shaver, Patti R.; Iyer, Rugmani P.; Whitehead, Kaitlin; McClung, Joseph M.; Vahdati, Ali; de Castro Brás, Lisandra E. (2023-05-15)
    Aims A peptide mimetic of a collagen-derived matricryptin (p1159) was shown to reduce left ventricular (LV) dilation and fibrosis after 7 days delivery in a mouse model of myocardial infarction (MI). This suggested p1159 ...

  • MODULATING MMP-9 SUBSTRATE PREFERENCE TO REDUCE INFLAMMATION POST-MI 

    Cakir, Sirin Nazan (East Carolina University, 2023-12-08)
    Worldwide, the prevalence of cardiovascular disease (CVD) is escalating, with myocardial infarction (MI) significantly contributing to the heightened rates of morbidity and mortality. Notably, one in every four MI patients ...