Browsing by Subject "Sarcoidosis"
Now showing items 1-4 of 4
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Expression of microRNA in Alveolar Macrophages Deficient in PPARy
(East Carolina University, 2014)The nuclear transcription factor Peroxisome proliferator-activated receptor gamma (PPARgamma) is a negative regulator of macrophage activation and inflammatory mediators. Alveolar macrophages of healthy individuals ... -
Gene-environment interactions in sarcoidosis
(East Carolina University, 2007-05)Susceptibility to most human diseases is polygenic, with complex interactions between functional polymorphisms of single genes governing disease incidence, phenotype, or both. In this context, the contribution of any ... -
Review: Carbon Nanotubes and Chronic Granulomatous Disease
(2014-06-23)Use of nanomaterials in manufactured consumer products is a rapidly expanding industry and potential toxicities are just beginning to be explored. Combustion-generated multiwall carbon nanotubes (MWCNT) or nanoparticles ... -
Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells
(2016-07-26)Abstract Background Sarcoidosis is a multisystem immuno-inflammatory disorder of unknown etiology that most commonly involves the lungs. We hypothesized that an unbiased ...