Browsing ECU Main Campus by Title
Now showing items 321-340 of 6390
-
AMP Deaminase 3 knockout mice and loss of mitochondrial proteins and enzyme activity during denervation atrophy
(East Carolina University, 2018-07-17)Muscle atrophy leads to decrements in muscle function, partly attributable to decreased mitochondrial content. One controller of mitochondrial content is AMP-activated protein kinase (AMPK), which when bound by AMP activates ... -
AMP Deaminase 3 overexpression regulates cellular energetics and signaling for PGC-1α activation.
(East Carolina University, 2017-06-02)Skeletal muscles undergoing atrophy have decreased [ATP], PGC-1[alpha] expression, and mitochondrial content. This combination of findings is unexpected because decreased [ATP] is often associated with greater [AMP] and ... -
AMP-activated protein kinase response to contractions and treatment with the AMPK activator AICAR in young adult and old skeletal muscle
(East Carolina University, 2009-05-01)One characteristic of aging skeletal muscle is a decline in mitochondrial function. Activation of AMP-activated protein kinase (AMPK)occurs in response to an increased AMP/ATP ratio,which is one potential result of ... -
AMPK regulates basal skeletal muscle capillarization and VEGF expression, but is not necessary for the angiogenic response to exercise
(East Carolina UniversityEast Carolina University, 2008-12-15)5 -AMP-activated protein kinase(AMPK)is a metabolic fuel sensor that monitors cellular energy charge, while the vasculature is important for maintaining cellular energy homeostasis. Mice with muscle-specific inactive AMPK ... -
AN ANALYSIS OF A PLAN TO IMPROVE THE GRADUATION RATES IN JOHNSTON COUNTY SCHOOLS
(East Carolina University, 2015-12-10)There have been limited qualitative case studies exploring effective strategies designed to improve graduation rates in rural school districts. Specifically, few studies have presented information based solely upon the ... -
AN ANALYSIS OF A STONE ARTIFACT CACHE FROM THE SHELOR SITE (31MG2051) IN MONTGOMERY COUNTY, NORTH CAROLINA
(East Carolina University, 2016-07-25)Prehistoric artifact cache discoveries are poorly understood archaeological phenomena. A few such occurrences consisting of groups of stone artifacts buried in forgotten underground pits are known in North Carolina. This ... -
AN ANALYSIS OF ALFRED SCHNITTKE'S POLYSTYLISM IN HIS STRING QUARTET NO. 3 (1983)
(East Carolina University, 2018-07-30)The study of polystylism and its role in the history of music is a relatively new idea; Alfred Schnittke is often regarded as the first true proponent of the term, and the bulk of his compositional output did not begin ... -
An Analysis of Dietary Habits of Young Adults Seeking Weight Loss and the Feasibility of a Modified Monitoring System Using Mobile Technology in Young Adults
(East Carolina University, 2016-04-29)With rates of overweight and obesity at the highest in recorded history, for the first time, it is expected that obese young adults will have a significantly lessened life expectancy compared to their non-obese counterparts ... -
AN ANALYSIS OF PUBLIC OPINION ON HUMAN TRAFFICKING LEGISLATION IN NORTH CAROLINA
(East Carolina University, 2022-12-08)Human trafficking presents an enormous issue for the United States and the state of North Carolina. Current legislative frameworks for labor and sex trafficking exist on the federal and state level, however the current ... -
An Analysis of Publicly Available Health Education Materials Designed for Migrant Farm Workers
(East Carolina University, 2021-05-28)BACKGROUND: In the United States, there are more than 3 million migrant or seasonal farm workers each year. The lack of legal protections, low pay, and often-dangerous work conditions lead to serious health inequities for ... -
AN ANALYSIS OF THE IMPACT OF mCLASS: READING 3D ON STUDENTS’ READING ACHIEVEMENT IN SECOND GRADE
(East Carolina University, 2015-04-28)The purpose of this program evaluation was to research North Carolina’s adoption of mClass: Reading 3D to determine program effectiveness, how teachers use student data from the program to improve instructional practices, ...