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Elucidating "Consumption" : Using Fluorescent Steroid Probes to Understand Host Cholesterol Utilization by Mycobacterium spp.
(East Carolina University, 2014)
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB) disease, is the leading cause of death due to bacterial infection worldwide, claiming nearly two million lives each year. Often, the immune system ...
A Bayesian Approach to Investigating Age-at-Death of Subadults in a Forensic Context
(East Carolina University, 2014)
Estimating age at death is among the first steps in the identification of an unknown individual. For subadults, dental formation stage remains the most accurate aging indicator due to minimal environmental impact. Even the ...
SPECTROSCOPIC INVESTIGATIONS OF BINDING MECHANISMS BETWEEN ANTIMICROBIAL PEPTIDES AND MODELS OF THE MEMBRANES OF PSEUDOMONAS AERUGINOSA AND KLEBSIELLA PNEUMONIAE
(East Carolina University, 2014)
The wide application of antibiotics goes back over sixty years to the first use of penicillin in the mid-1940s. Antimicrobial agents have well-documented activity and have played a significant role in defending against ...
An Archaeological Exploration of a Settlement at Dixie Plantation, Hollywood, SC
(East Carolina University, 2014)
The College of Charleston's Dixie Plantation in Hollywood, SC is located 19 miles west of the College of Charleston's main campus in downtown Charleston. Dixie Plantation was formerly an 18th and 19th century rice and ...
MEDICAL PROVIDERS' VIEWS OF MEDICALLY UNEXPLAINED ILLNESS AND MEDICALLY UNEXPLAINED SYMPTOMS
(East Carolina University, 2013)
Patients who present with medically unexplained illnesses or medically unexplained symptoms (MUI/S) tend to be higher utilizers of healthcare services and have significantly greater healthcare costs than other patients, ...
A BRIEF MOTIVATIONAL INTERVIEWING INTERVENTION (SIESTA) FOR ADOLESCENT SLEEP : EFFECTS ON NEUROCOGNITION AND SLEEP-RELATED BEHAVIOR
(East Carolina University, 2013)
Several studies have described sleep characteristics of adolescents, concluding that adolescent sleep lacks duration, quality, and consistency. Due to behavioral, environmental and biological changes, adolescents tend to ...
SPATIAL EXPRESSION OF MATRIX AND MATRIX RECEPTOR PROTEINS IN THE DEVELOPING SYNOVIAL JOINT
(East Carolina University, 2013)
Little is understood about the complex spatial and temporal molecular interactions necessary to form a fully functional synovial joint. Understanding molecular pathways and signaling within the developing joint continues ...
A quantitative and nondestructive method for determining the degradation of waterlogged archaeological wood
(East Carolina University, 2013)
Archaeological artifacts are an essential part of preserving history and culture, and can be valuable tools for enhancing education and contributing economic benefits through tourism. Of the artifacts that one may encounter, ...
Undergraduates' Perceptions of High School Experiences
(East Carolina University, 2013)
Sexual harassment is common in high schools and research has provided in-depth information about the frequency and types of sexually harassing behaviors. Female students experience more sexual harassment and are more ...