Browsing Physiology by Author "McClung, Joseph M."
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Muscle cell derived angiopoietin-1 contributes to both myogenesis and angiogenesis in the ischemic environment
McClung, Joseph M.; Reinardy, Jessica L.; Mueller, Sarah B.; McCord, Timothy J.; Kontos, Christopher D.; Brown, David A.; Hussain, Sabah N. A.; Schmidt, Cameron A.; Ryan, Terence E.; Green, Thomas D. (2015-05)Recent strategies to treat peripheral arterial disease (PAD) have focused on stem cell based therapies, which are believed to result in local secretion of vascular growth factors. Little is known, however, about the role ... -
PFKFB3-Mediated Glycolysis Rescues Myopathic Outcomes in the Ischemic Limb
McClung, Joseph M.; Ryan, Terence E.; Spangenburg, Espen E.; Schmidt, Cameron A.; Tarpey, Michael D.; Amorese, Adam J.; Yamaguchi, Dean J.; Goldberg, Emma J.; Iñigo, Melissa M.R.; Karnekar, Reema; Brophy, Patricia; Green, Thomas D.; Neufer, P. Darrell; Fisher-Wellman, Kelsey H.; Spangenburg, Espen E. (2020-09-17) -
PFKFB3-Mediated Glycolysis Rescues Myopathic Outcomes in the Ischemic Limb
Spangenburg, Espen; Ryan, Terence E.; McClung, Joseph M. (2020-09-17) -
Physiologic Determinants of Ischemic Skeletal Muscle Pathophysiology
Schmidt, Cameron Alan (East Carolina University, 2018-11-29)Lower limb peripheral arterial occlusive disease (PAD) has major impacts on patient quality of life and, in its most severe form, carries a significant risk of mortality. The canonical approach to PAD research has been ... -
Subcellular Proteomics Combined with Bioenergetic Phenotyping Reveals Protein Biomarkers of Respiratory Insufficiency in the Setting of Proofreading-Deficient Mitochondrial Polymerase
McClung, Joseph M.; McLaughlin, Kelsey L.; Kew, Kimberly A.; Fisher-Wellman, Kelsey H. (2020-02-27) -
Targeted Expression of Catalase to Mitochondria Protects Against Ischemic Myopathy in High-Fat Diet-Fed Mice
Spangenburg, Espen; Ryan, Terence E.; Schmidt, Cameron A.; Green, Thomas D.; Neufer, P. Darrell; McClung, Joseph M. (2016-06-09) -
Temporal Association Between Ischemic Muscle Perfusion Recovery and the Restoration of Muscle Contractile Function After Hindlimb Ischemia
McClung, Joseph M.; Goldberg, Emma J.; Schmidt, Cameron A.; Green, T. D.; Karnekar, R.; Yamaguchi, D. J.; Spangenburg, E. E. (2019-06-28) -
Tissue-Specific Characterization of Mitochondrial Branched-Chain Keto Acid Oxidation Using a Multiplexed Assay Platform
McClung, Joseph M. (2019-05-31)