Now showing items 1-8 of 8
Muscle Mitochondria in Vascular Disease: A Novel Genetic Target for Limb Salvage
(East Carolina University, 2022-04-19)
Peripheral arterial occlusive disease (PAD) is a manifestation of systemic atherosclerosis defined by an occlusion in the peripheral arteries, most commonly those supplying blood to the lower extremities. Chronic limb ...
Why Does Exercise â€œTriggerâ€? Adaptive Protective Responses in the Heart?
Numerous epidemiological studies suggest that individuals who exercise have decreased cardiac morbidity and mortality. Pre-clinical studies in animal models also find clear cardioprotective phenotypes in animals that ...
The â€œGoldilocks Zoneâ€? from a redox perspectiveâ€”Adaptive vs. deleterious responses to oxidative stress in striated muscle
Consequences of oxidative stress may be beneficial or detrimental in physiological systems. An organ system's position on the “hormetic curve” is governed by the source and temporality of reactive oxygen species (ROS) ...