Now showing items 1-5 of 5
The role of cardiac mitochondria in myocardial ischemia/reperfusion injury
(East Carolina University, 2012)
Cardiovascular disease (CVD) exerts economic and humanitarian costs that are unparalleled by any other disease. Of the many etiologies of CVD, myocardial infarction accounts for over 50% of the associated mortality and ...
EphA2-receptor deficiency exacerbates myocardial infarction and reduces survival in hyperglycemic mice
Background We have previously shown that EphrinA1/EphA expression profile changes in response to myocardial infarction (MI), exogenous EphrinA1-Fc administration following MI positively influences wound healing, and ...
Physiologic Determinants of Ischemic Skeletal Muscle Pathophysiology
(East Carolina University, 2018-11-29)
Lower limb peripheral arterial occlusive disease (PAD) has major impacts on patient quality of life and, in its most severe form, carries a significant risk of mortality. The canonical approach to PAD research has been ...
INTRINSIC EXERCISE CAPACITY ON HIND LIMB ARTERIAL LIGATION: DIFFERENTIAL IMPACT OF ACTIVE EXERCISE AND ANDROGEN SIGNALING ON POST-ISCHEMIC RECOVERY
(East Carolina University, 2018-12-21)
Peripheral arterial disease (PAD) is a common disease that is frequently caused by atherosclerosis and associated thrombosis, leading to a decrease in the blood supply to the lower extremities. PAD has various treatment ...
Cardiovascular Outcomes Following Xenobiotic Pulmonary Exposures
(East Carolina University, 2017-07-06)
Cardiovascular disease remains the leading cause of mortality in the developed world. Over the past decades, investigations have demonstrated that pulmonary exposure to xenobiotic particulate matter promotes and exacerbates ...