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INTRINSIC EXERCISE CAPACITY ON HIND LIMB ARTERIAL LIGATION: DIFFERENTIAL IMPACT OF ACTIVE EXERCISE AND ANDROGEN SIGNALING ON POST-ISCHEMIC RECOVERY
(East Carolina University, 2018-12-21)
Peripheral arterial disease (PAD) is a common disease that is frequently caused by atherosclerosis and associated thrombosis, leading to a decrease in the blood supply to the lower extremities. PAD has various treatment ...
Muscle Mitochondria in Vascular Disease: A Novel Genetic Target for Limb Salvage
(East Carolina University, 2022-04-19)
Peripheral arterial occlusive disease (PAD) is a manifestation of systemic atherosclerosis defined by an occlusion in the peripheral arteries, most commonly those supplying blood to the lower extremities. Chronic limb ...
The “Goldilocks Zone� from a redox perspective—Adaptive vs. deleterious responses to oxidative stress in striated muscle
(2014-09)
Consequences of oxidative stress may be beneficial or detrimental in physiological systems. An organ system's position on the “hormetic curve” is governed by the source and temporality of reactive oxygen species (ROS) ...