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Linking energy state to redox environment through mitochondrial redox circuits
(East Carolina University, 2016-11-16)
Mitochondria are the primary producers of intracellular H2O2, an oxidant signaling molecule that has gained attention for its role in normal physiological processes and disease etiologies such as skeletal muscle insulin ...
Cardioprotective mechanisms targeting thiol redox homeostasis and mitochondrial bioenergetics
(East Carolina University, 2016-05-03)
Coronary heart disease is a leading cause of death in the United States, totaled mostly by deaths associated with myocardial infarction and fatal ventricular arrhythmias. The inability to predict the occurrence of these ...