Browsing College of Allied Health Sciences by Author "Morton, Cynthia C."
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A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunction
Robertson, Nahid G.; Jones, Sherri M.; Sivakumaran, Theru A.; Giersch, Anne B. S.; Jurado, Sara A.; Call, Linda M.; Miller, Constance E.; Maison, Stephane F.; Liberman, M. Charles; Morton, Cynthia C. (East Carolina University, 2008-11-01)Mutations in COCH (coagulation factor C homology) are etiologic for the late-onset, progressive, sensorineural hearing loss and vestibular dysfunction known as DFNA9. We introduced the G88E mutation by gene targeting into ...