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Now showing items 31-40 of 65
THE ROLE OF THE ALVEOLAR MACROPHAGE IN CARBON NANOTUBE ELICITED MURINE MODEL OF PULMONARY GRANULOMATOUS INFLAMMATION
(East Carolina University, 2018-11-29)
Pulmonary sarcoidosis is a debilitating inflammatory condition characterized by the presence of granulomatous lesions throughout the lung. Granulomas are a physiological response to inhaled antigens or particulate matter ...
Nutrient contributions from septic systems in nutrient-sensitive watersheds: Quantifying nutrient inputs, reduction methods, and economic feasibility
(East Carolina University, 2019-04-30)
Eutrophication of surface waters is a global issue threatening aquatic ecosystems and recreational opportunities. Nutrient management strategies exist to reduce nutrient inputs from various sources; however, septic systems ...
Beyond the Waters' Edge: Complexity and Conservation Management of Underwater Cultural Heritage by Public Agencies in North Carolina
(East Carolina University, 2019-04-29)
This study used a mixed methods case study approach to investigate the nature and behavior of the system in North Carolina within which managers in its public agency for Archives and History have implemented public policy ...
Is this Ship Covered?: The Intersection of Law, Geography, and Management of Sunken Military Craft
(East Carolina University, 2019-12-10)
The legal framework protecting historic shipwrecks and other underwater cultural heritage in the United States is largely fragmented and not always effective. Factors that may influence the legal protection afforded a ...
Molecular characterization of the activation domain of the HTLV-1 HBZ protein and its interaction with the KIX domain of the cellular transcriptional coactivators p300 and CBP
(East Carolina University, 2010)
The complex retrovirus human T-cell leukemia virus type I (HTLV-1) is the causative agent of adult T-cell leukemia (ATL). Deregulation of cellular transcription is thought to be a key event in virally-mediated T-cell ...
Decisions Under Duress: Influences on Official Decision Making During Superstorm Sandy
(East Carolina University, 2015-12-08)
During impending storms, emergency managers and politicians are tasked with the difficult decision of whether or not to issue evacuation orders for their area. This study uses Superstorm Sandy as a case study and investigates ...
Incorporating Migration and Local Movement Patterns into Management Strategies for Spiny Dogfish (Squalus acanthias)
(East Carolina University, 2015-12-15)
The overall purpose of this dissertation is to increase understanding of migration and movement behaviors associated with a highly migratory elasmobranch species. In particular, I seek to determine whether sufficient ...
Tight junction claudin-7 protein modulates multiple processes of cancer progression in human lung cancer cells
(East Carolina University, 2016-05-03)
Carcinogenesis usually consists of cancer initiation, promotion, and progression. Several tight junction claudin proteins have been identified as tumor suppressors or activators during cancer development. As apical proteins, ...
Reproductive Toxicity of Crude oil-Dispersant Mixture in Caenorhabditis elegans
(East Carolina University, 2016-05-05)
As crude oil remains a vital natural resource for the energy need of the world, environmental crude oil spills continue to be a health risk to human beings and ecological systems. During clean-up efforts, surfactant-like ...
Issues of Criticism and Authorship in Arthur Miller's All My Sons : A Bakhtinian Reading
(East Carolina University, 2011)
All my Sons may not be Miller's most known work today, but it is the play that brought him recognition as a playwright. Since its first production, in 1947, critics have assessed the play's content and characters through ...