Browsing Dissertations and Theses by Title
Now showing items 1089-1108 of 4831
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Deletion of LPCAT3 Promotes Enhanced Insulin Signaling in Skeletal Muscle
(East Carolina University, 2015-12-15)Aberrant lipid metabolism has been linked to skeletal muscle insulin resistance. The exact identity of the lipid species that promote skeletal muscle insulin resistance among the human population remains unclear. In this ... -
Delination of Coastal Shark Habitat within North Carolina Waters Using Acoustic Telemetry, Fisher-Independent Surveys, and Local Ecological Knowledge
(East Carolina University, 2016-07-20)Knowledge of shark habitat preferences and use patterns is important to effectively manage shark fisheries and account for interactions between sharks and species targeted by other fishery management or conservation efforts. ... -
DELINEATING THE MECHANISM OF AGGREGATE OR BIOFILM FORMATION IN THE LYME DISEASE SPIROCHETE BORRELIA BURGDORFERI
(East Carolina University, 2021-07-14)Borrelia burgdorferi, the spirochete causing Lyme disease, is transmitted to a vertebrate host by the bite of an infected Ixodes scapularis tick. The spirochete develops antibiotic resistance in humans likely due to the ... -
DELINEATING THE ROLE OF SOLUBLE CD25 AS AN IMMUNOREGULATORY MOLECULE THAT PROMOTES A LOW-ZONE IL-2 SIGNALING ENVIRONMENT FAVORABLE FOR THE SELECTION OF CD25HIGH FOXP3HIGH T CELLS
(East Carolina University, 2021-07-22)Autoimmune diseases develop due to the breakdown of tolerogenic mechanisms that normally maintain immune homeostasis. CD4+ CD25+ FOXP3+ regulatory T cells (Tregs) are critical in the maintenance of tolerance and the ... -
Delineating Wastewater Contaminant Plumes from On-Site Wastewater Treatment Systems in the North Carolina Coastal Plain using Electromagnetic Induction
(East Carolina University, 2016-08-18)In North Carolina, wastewater-derived nutrients and harmful bacteria threaten public health and reduce water quality for many surface water bodies. North Carolina uses ~ 2 million on-site wastewater treatment systems, yet ... -
[Delta]-catenin: implications in prostate cancer progression
(East Carolina University, 2014)Prostate cancer (PCa) is the most commonly diagnosed cancer and the second most common cause of cancer death among men in the US. Due to the advances in research, the ability to detect and cure PCa has improved and led to ... -
A Democratic Art
(East Carolina University, 2013)This is a report on my creative research and it is written in support of my thesis exhibition entitled A Democratic Art. This thesis is an investigation into the ways printmaking is celebrated within the printmaking ... -
Demystifying the Huntress: Exploring the Experiences of Women Hunters in Eastern North Carolina
(East Carolina University, 2017-07-13)The hunter occupies a special place in the system of human-animal interactions. When entering the natural world of wildlife each hunter learns to navigate this world in his or her own way. Hunters aid wildlife management ... -
Dengue risk assessment
(East Carolina University, 2015)Dengue fever is the most prevalent vector borne disease in the world with over 3.6 billion people at risk and one billion new infections (including one million deaths) recorded annually. Risk assessments showing the impact ... -
Denise Giardina's Storming Heaven: Cultural Marginalization in Appalachia
(East Carolina University, 2017-05-03)Using Everett Verner (E.V.) Stonequist's sociological constructs of marginalization and marginal personalities, this study focuses on the extent of marginalization as depicted in Appalachian novelist Denise Giardina's ... -
DERIVATION OF TOLEROGENIC THERAPEUTIC VACCINES FOR MOUSE MODELS OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
(East Carolina University, 2012)Multiple sclerosis (MS) is a chronic inflammatory disease that results in autoimmune demyelination of the human central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is a widely-studied animal ... -
Describing Nitrogen Dynamics in Eastern North Carolina Waterfowl Impoundments by Combining Field-Scale and Laboratory-Scale Based Approaches
(East Carolina University, 2018-08-01)Waterfowl impoundments are wetlands that are hydrologically managed to provide food and habitat for migratory bird populations. Certain impoundment types have recently been found to export nitrogen (N) loads during seasonally ... -
Describing the Relationship Between Psychosocial Distress and Extent of Criminal Justice System Involvement for Men and Women in a Sober Living Environment
(East Carolina University, 2016-04-14)Symptoms of mental health and substance use disorders are prevalent for individuals involved in the criminal justice system and are associated with both costs to society and the individual. The purpose of this study was ...