Browsing Dissertations and Theses by Submit Date
Now showing items 1-20 of 2618
-
Modern and Classic Quantum Chemistry: Modeling Rhodium-Catalyzed Hydroacylation with Advanced Tools and the Development and Application of Software to Examine Simple Bonding Interactions in a Basis of Molecular Fragments
(East Carolina University, 8/5/2020)In this dissertation, both modern and classic computational methods are utilized to examine two problems of interest in the field of chemistry. The first problem involves a complex rhodium-catalyzed hydroacylation reaction ... -
BUILDING A BIOPSYCHOSOCIAL-SPIRITUAL MODEL FOR PREDICTING ADHERENCE AMONG CANCER SURVIVORS
(East Carolina University, 8/5/2020)Advancements in medicine and preventive care have led to the greatest number of cancer survivors (CSs) in history. Although surviving cancer may be more achievable today, the care required for CSs persists beyond active ... -
FUNCTIONS OF CLAUDIN-7 IN THE SELF-RENEWAL OF INTESTINAL EPITHELIUM
(East Carolina University, 8/5/2020)Tight junctions (TJ) are located at the most apical region of the junctional complex and contain many integral membrane proteins. Claudin 7 (Cldn7) is a TJ membrane protein located at the apical TJ and basolateral side of ... -
GENE EXPRESSION IN RESPONSE TO MECHANICAL LOADING ON THE ANTERIOR CRUCIATE LIGAMENT
(East Carolina University, 8/5/2020)Many tissues in the body, especially bone, have exhibited adaptive responses to lowmagnitude, high frequency mechanical loading. However, the response of ligament to these types of mechanical loads is not well understood. ... -
THE IMPACT OF PARENTAL INCARCERATION ON EMERGING ADULT’S DEPRESSION, ANXIETY, AND SUBSTANCE ABUSE BEHAVIOR
(East Carolina University, 8/5/2020)This study was conducted to understand the impact parental incarceration has on emerging adult’s depression, anxiety, and substance abuse behavior. Researchers were also interested to see if resilience was a moderator of ... -
Words that Hurt: Trait Aggression and Gossiping Behaviors
(East Carolina University, 8/5/2020)This study sought to assess the association between trait aggression and gossiping behaviors. Gossip is typically regarded as a negative behavior that often leads to negative feelings being felt by the target of the gossip. ... -
FORAMINIFERAL COMMUNITY DYNAMICS OF THE CHESAPEAKE GROUP, CALVERT CLIFFS, MARYLAND, USA
(East Carolina University, 8/5/2020)The long-term impact of climate and sea-level change on marine communities can be documented using the fossil record of well-studied, and widely distributed organisms such as benthic foraminifera. The Calvert and Choptank ... -
Characterizing the Binding of Ca2+, Cd2+, and Pb2+ to EF-hand Peptide V of Calbindin D28K and EF-hand Peptides III and IV of Human Cardiac Troponin C Using CD, ITC, and Fluorescence Spectroscopy
(East Carolina University, 8/5/2020)Calcium-binding EF-hand proteins are ubiquitous in the cell and are essential for many biological functions such as muscle contraction and cell signaling. Divalent cadmium, Cd2+, and lead, Pb2+ are toxic metal ions that ... -
EXPLORING THE RELATIONSHIP BETWEEN COPARENTING QUALITY, PARENTING STRESS, PARENTING EFFICACY AND INCARCERATION
(East Carolina University, 8/5/2020)Data was gathered from 232 participants that were recruited to participate in this study as part of a larger, federally-funded healthy marriage and relationship education initiative in a southern state. The aims of the ... -
Effects of aerobic exercise training on arterial stiffness and autonomic function in obese adults at-risk of cardiovascular disease and type 2 diabetes
(East Carolina University, 8/5/2020)Obesity is a major risk factor for cardiovascular disease (CVD), CVD mortality, and type 2 diabetes. Arterial stiffness and autonomic dysfunction are independent predictors of CVD and type 2 diabetes. Moreover, African ... -
Characterization of the glucose transporters responsible for mechanical overloadstimulated glucose uptake in mouse skeletal muscle
(East Carolina University, 8/5/2020)Resistance exercise training is a recommended form of physical activity for people with type 2 diabetes due to its ability to increase skeletal muscle glucose uptake. Understanding how resistance training controls muscle ... -
THERE’S TWO SIDES TO EVERY STORY: EXPANDING THE NOMOLOGICAL NETWORK OF BURNOUT THROUGH THE PERSON-ENVIRONMENT INTERACTION
(East Carolina University, 8/5/2020)Burnout is a psychological syndrome consisting of emotional exhaustion, cynicism, and reduced personal accomplishment. It is associated with a depletion of intrinsic resources that results from prolonged exposure to ... -
Investigating Membrane Protection of Red Blood Cells in the Presence of Mono and Disaccharides at Hypothermic Storage Conditions
(East Carolina University, 8/5/2020)The maximum approved storage time of red blood cells under hypothermic conditions is 42 days when treated with an appropriate additive solution. Here, we investigated the possible protective properties of various mono and ... -
Influence of Perivascular Adipose Tissue on Central Arterial Mechanics and Hemodynamics: A Parametric Fluid-Structure Interaction Analysis
(East Carolina University, 8/5/2020)This study aims to evaluate the biomechanical influence of perivascular adipose tissue (PVAT) on arterial wall mechanics and hemodynamics, which are key regulators in cardiovascular disease progression. Fluid-structure ... -
EFFECTS OF MEDIA USE ON BEHAVIORAL INHIBITION IN PRESCHOOLERS
(East Carolina University, 8/5/2020)Previous research suggests that there is a link between children’s media use and their executive function. The present study aimed to assess preschool-aged children’s media use and to determine if different levels of media ... -
HEALTH-PROMOTING LEADERSHIP AND EMPLOYEE LEAVE: THE POTENTIAL MODERATING EFFECT OF PSYCHOLOGICAL DETACHMENT
(East Carolina University, 8/5/2020)The current study was designed to examine the relationships between health-promoting leadership (HPL), psychological detachment, willingness to take sick leave, vacation leave, and FMLA leave, and presenteeism. A self-report ... -
Thermodynamic and Structural Characterization of Cd(II) binding to human cardiac troponin C: Using Mutants and Truncated Constructs to Elucidate Cd(II) binding sites
(East Carolina University, 8/5/2020)Many biological processes rely on the presence of essential metals; therefore, maintaining the concentration of metals is paramount to homeostasis. Cadmium, Cd(II), is a toxic heavy metal that can disturb this delicate ... -
MECHANISMS OF LEFT VENTRICULAR REMODELING IN PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS
(East Carolina University, 8/5/2020)Cardiac remodeling is composed of molecular, cellular, and interstitial changes in the cardiac tissue that affect the size, shape, and function of the heart. There are two types of cardiac remodeling: physiological and ... -
IMPACTS OF A BRIEF, PILOT SELF-COMPASSION PROGRAM FOR WOMEN WITH OVERWEIGHT/OBESITY AND INTERNALIZED WEIGHT BIAS
(East Carolina University, 8/5/2020)Internalization of weight bias occurs when one believes negative weight-related stereotypes to be true of themselves, such as believing that one is deserving of disrespect, or unworthy of partnership due to weight status ... -
CHARACTERIZING THE STIGMA TRANSCRIPTOME OF LEPTOSIPHON JEPSONII
(East Carolina University, 8/5/2020)The majority of angiosperm species are hermaphroditic, containing both male and female reproductive organs on the same plant. This introduces the possibility of reproducing through self-fertilization (selfing) in flowering ...