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Notch 3 Affects Chemoresistance in Colorectal Cancer via DNA Base Excision Repair Enzymes
(East Carolina University, 2017-07-28)
Approximately 1.2 million cases of colorectal cancer (CRC) arise each year, and 40-50% of CRC patients will reach metastasis. The Notch pathway is known to be dysregulated in CRC, and its relationship with DNA repair ...
Automatic SQL query generation
(East Carolina University, 2017-07-19)
Automatic generation of questions for learning assessment has been an area of research interest for long. The advent of Massive Open Online Courses (MOOCs) as well as the goal of providing immediate contextualized feedback ...
Thoughts on Temporal Perception's Relativity in Grisey's Vortex Temporum and Voss's Perspectives
(East Carolina University, 2017-07-21)
This thesis centers around a comparative analysis between an instrumental work, Vortex Temporum (1995), by Gérard Grisey (1946-98), and a mixed media work by Emerson Voss (b. 1991), Perspectives (2017). This essay articulates ...
Bermuda: A Case Study on the Impact of Maritime Introduced Contagions and the Yellow Fever Epidemics of the Nineteenth Century
(East Carolina University, 2017-12-01)
Contagion is an unfortunate consequence of conflict and trade. Bermuda's isolation and rich history of maritime commercial and naval activities provides an excellent case study to review the impact of trade on the introduction ...
The dish ran away with the spoon : revisiting unprovenienced foodways artifacts from eighteenth century Spanish fleet shipwrecks
(East Carolina University, 2017-12-06)
The Spanish empire was the first European power to establish permanent settlements that flourished as New World colonies on several of the Caribbean islands and coasts of North America. The distance between Spain and the ...
Illuminating the Lighthouse: An Historical and Archaeological Examination of the Causes and Consequences of Economic and Social Change at the Currituck Beach Light Station
(East Carolina University, 2017-11-29)
The purpose of this project was to gather historical and archaeological data to illuminate potential relationships between economic and social investment in lighthouse complexes, and enhance an understanding of the multitude ...
TEXTILE ARTS AS A COPING MECHANISM FOR AN ADOLESCENT WHO HAS EXPERIENCED LIFE STRESSORS
(East Carolina University, 2017-12-06)
The current case study explores how textile arts can be used as a coping mechanism for an adolescent who has experienced life stressors, including a chronic illness and repeated hospitalizations. The adolescent participant ...
William S.W. Ruschenberger: A Study of an American Naval Officer in the Nineteenth Century
(East Carolina University, 2017-12-07)
This is a case study of a naval surgeon whose experience as surgeon and diplomat demonstrates the intentional expansionist efforts of the United States in the early nineteenth century, much earlier than emphasized in the ...
Keyboarding Without Tears to Improve the Keyboarding Skills of Elementary Students
(East Carolina University, 2017-12-06)
In order to meet the demands of the technology-driven world, students must demonstrate keyboarding competency as early as in kindergarten. Common Core Standards now have technology requirement starting with third grade ...
Modeling Groundwater Inundation Under Sea-Level Rise Scenarios in the Surficial Aquifer of Bogue Banks, North
(East Carolina University, 2017-12-06)
Bogue Banks in North Carolina is expected to be impacted by sea-level rise, but the impact on the subsurface groundwater system is not well understood. A three-dimensional Visual MODFLOW steady-state model and ArcGIS 10.3 ...