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TLR-4 agonism induces CD25+ MHCIIhigh dendritic cells in association with tolerogenic antigen recognition
(East Carolina University, 2022-12-06)
Autoimmune disease is a result of the breakdown in immunological self-tolerance leading to destruction of self-tissues mediated by the aberrant immune attack. In Multiple Sclerosis (MS), CD4+ T cells mediate destruction ...
An Augmented Counseling Approach on Fear of Crime and Self-Efficacy in Older Adults
(East Carolina University, 2022-07-28)
Fear of crime research notes two strong predictors of fear are fear of crime and perceived risk of victimization. Adults 65 years of age and older report a higher fear of crime than younger age groups. The effects of fear ...
Kinin B1 Receptor Mediated Mechanisms in Hypertension
(East Carolina University, 2022-08-15)
Hypertension continues to cause a burden on the global population as there are growing numbers of patients who present with treatment resistant hypertension. The etiology of hypertension is considered complex and multifactorial ...
Counselors’ Attitudes Toward Sex Trafficking: A Quantitative, National Analysis
(East Carolina University, 2022-06-03)
For more than 20 years, the pervasive problem of sex trafficking has garnered increasing attention in research, advocacy, and legislation. The cumulative research focuses on the trafficking of women and girls based on the ...
Characterization of the glucose transport mechanism responsible for mechanical overload- and acute injury-stimulated skeletal muscle glucose uptake
(East Carolina University, 2022-06-24)
Skeletal muscle is a highly adaptable tissue. In response to stimuli such as resistance exercise training or trauma/injury, muscle glucose uptake is stimulated to fuel the energetic and biosynthetic demands of growth, ...
Genetic regulation of maize floral development - insights from the transcriptome and translatome
(East Carolina University, 2022-06-24)
Flowers are produced by floral meristems, groups of stem cells that give rise to floral organs. In grasses, including the major cereal crops, flowers (florets) are contained in spikelets, which contain one to many florets, ...
Lèvy noise induced steady states
(East Carolina University, 2022-06-08)
Systems far from equilibrium organize themselves to accommodate energy throughput. It is also in these nonequilibrium systems where noise has often been found to follow alpha-stable distributions, commonly called Lévy ...
SAFE HAVENS AND HOT SPOTS: IONIZING RADIATION IN MARTIAN PERMAFROST AND ITS INFLUENCE ON THE SURVIVAL OF ANCIENT LIFE
(East Carolina University, 2022-06-20)
Permafrost on Mars is considered a primary target for the search for life. On a microscopic scale permafrost is highly non-uniform and the effective radiation dose absorbed by a microbe, and thus its survival probability, ...
INVESTIGATING MECHANISMS REGULATING MAMMALIAN SPERMATOGONIAL DIFFERENTIATION AND MEIOTIC INITIATION
(East Carolina University, 2022-06-27)
Spermatogonia differentiation and meiotic initiation are complex processes essential for male fertility. Despite knowing for nearly 60 years that retinoic acid (RA) is instrumental for successful production of functional ...
Kinin B1 Receptor Mediated Mechanisms in Hypertension
(East Carolina University, 2022-08-15)
Hypertension continues to cause a burden on the global population as there are growing numbers of patients who present with treatment resistant hypertension. The etiology of hypertension is considered complex and multifactorial ...