Browsing College of Health and Human Performance by Author "Dohm, G. Lynis"
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Modulation of IKKβ with AMPK Improves Insulin Sensitivity in Skeletal Muscle
Bikman, Benjamin Thomas (East Carolina University, 2008-11)Activation of the insulin receptor substrate (IRS)-1 is necessary for proper transduction of the insulin signal. IRS-1 serine312(human)/307(rodent) phosphorylation, however, results in disruption of this signal and subsequent ...