Browsing College of Health and Human Performance by Author "Zwetsloot, Kevin A."
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AMPK regulates basal skeletal muscle capillarization and VEGF expression, but is not necessary for the angiogenic response to exercise
Zwetsloot, Kevin A.; Westerkamp, Lenna M.; Holmes, Burton F.; Gavin, Timothy Patrick (East Carolina UniversityEast Carolina University, 2008-12-15)5 -AMP-activated protein kinase(AMPK)is a metabolic fuel sensor that monitors cellular energy charge, while the vasculature is important for maintaining cellular energy homeostasis. Mice with muscle-specific inactive AMPK ... -
No difference in the skeletal muscle angiogenic response
Gavin, Timothy Patrick; Ruster, Rebecca S.; Carrithers, John A.; Zwetsloot, Kevin A.; Kraus, Raymond M.; Evans, Christopher A.; Knapp, Deborah J.; Drew, James L.; McCartney, Jennifer S.; Garry, Joseph P.; Hickner, Robert C. (East Carolina University, 2007-11)Ischaemia-induced skeletalmuscle angiogenesis is impaired in aged compared with young mice. In humans, vascular endothelial growth factor (VEGF) mRNA and protein following an acute exercise bout are lower in aged compared ...