Now showing items 1-3 of 3

  • Effect of Acute Exercise or Fasting on Mitochondrial Function and High Fat Diet-Induced Insulin Resistance 

    Kwon, Oh Sung (East Carolina University, 2009)
    A high-fat diet leads to an accumulation of lipid in skeletal muscle, and the development of both mitochondrial dysfunction and insulin resistance. Recently, our lab reported that lipid overload leads to elevated ...
  • Metabolic Flexibility in Non-Obese Individuals 

    Khang, Nkaujyi (East Carolina University, 2020-06-22)
    Human skeletal muscle cells have been used as a tool to study and understand skeletal muscle metabolism due to their retention in characteristics from their donor. Metabolic flexibility is the ability to respond or adapt ...
  • Metabolic Inflexibility in Skeletal Muscle With Obesity 

    Boyle, Kristen E. (East Carolina University, 2009)
    The skeletal muscle of obese individuals has a reduced capacity to oxidize lipids. The hypothesis to be tested in this dissertation is that the ability to regulate lipid oxidation in response to lipid exposure is impaired ...