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Deletion of LPCAT3 Promotes Enhanced Insulin Signaling in Skeletal Muscle
(East Carolina University, 2015-12-15)
Aberrant lipid metabolism has been linked to skeletal muscle insulin resistance. The exact identity of the lipid species that promote skeletal muscle insulin resistance among the human population remains unclear. In this ...
SKELETAL MUSCLE METABOLIC FLEXIBILITY IMPAIRMENTS IN RESPONSE TO LIPID WITH OBESITY : EFFECT OF EXERCISE TRAINING
(East Carolina University, 2012)
Obese individuals exhibit skeletal muscle metabolic inflexibility by failing to increase fat oxidation and genes linked with mitochondrial biogenesis in response to a high-fat diet (HFD) and lipid incubation in cell culture. ...