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Effects of a high fat diet and/or overload on striated muscle structure, function, or metabolism
(East Carolina University, 2020-12-03)
Consumption of a high fat diet combined with physical inactivity is associated with many adverse health effects including obesity, insulin resistance/type 2 diabetes, and cardiovascular disease/myocardial infarction. The ...
Characterization of the glucose transporters responsible for mechanical overloadstimulated glucose uptake in mouse skeletal muscle
(East Carolina University, 8/5/2020)
Resistance exercise training is a recommended form of physical activity for people with type 2 diabetes due to its ability to increase skeletal muscle glucose uptake. Understanding how resistance training controls muscle ...
Metabolic Flexibility in Non-Obese Individuals
(East Carolina University, 2020-06-22)
Human skeletal muscle cells have been used as a tool to study and understand skeletal muscle metabolism due to their retention in characteristics from their donor. Metabolic flexibility is the ability to respond or adapt ...
Characterization of the glucose transport mechanism responsible for mechanical overload- and acute injury-stimulated skeletal muscle glucose uptake
(East Carolina University, 2022-06-24)
Skeletal muscle is a highly adaptable tissue. In response to stimuli such as resistance exercise training or trauma/injury, muscle glucose uptake is stimulated to fuel the energetic and biosynthetic demands of growth, ...