• Find People
  • Campus Map
  • PiratePort
  • A-Z
    • About
    • Submit
    • Browse
    • Login
    View Item 
    •   ScholarShip Home
    • Academic Affairs
    • Thomas Harriot College of Arts and Sciences
    • Chemistry
    • View Item
    •   ScholarShip Home
    • Academic Affairs
    • Thomas Harriot College of Arts and Sciences
    • Chemistry
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of The ScholarShipCommunities & CollectionsDateAuthorsTitlesSubjectsTypeDate SubmittedThis CollectionDateAuthorsTitlesSubjectsTypeDate Submitted

    My Account

    Login

    Statistics

    View Google Analytics Statistics

    Solvent and Solubility Effects on Quinone Ratios

    Thumbnail
    View/ Open
    Duffy_ecu_0600M_10735.pdf (414.5Kb)

    Show full item record
    Author
    Duffy, Brian
    Abstract
    Monoquinones and diquinones are a biologically and chemically important class of compounds that can be found in numerous natural products such as: thymoquinone, oosporein, coenzyme Q, embelin and the respective dimer, biembelin. These 1, 4-benzoquinone derivatives exhibit prominent pharmacological applications such as antibiotic, anti-tumor, anti-malarial, anti-coagulant, and anti-convulsant activity.    Though quinones can be prepared by a variety of processes, they are most commonly synthesized through the treatment of hydroquinone dimethyl ethers with ceric ammonium nitrate (CAN). However, this can lead to an unpredictable mixture of monoquinone and diquinone as the products. This project has investigated the effect of solvent and substrate water solubility on monoquinone / diquinone product ratios with the aim of being able to consistently and predictably favor one (monoquinone or diquinone) over the other.  
    URI
    http://hdl.handle.net/10342/4003
    Subject
     Chemistry; Chemistry, Organic; Diquinone; Quinone; Synthesis; Organic chemistry 
    Date
    2012
    Citation:
    APA:
    Duffy, Brian. (January 2012). Solvent and Solubility Effects on Quinone Ratios (Master's Thesis, East Carolina University). Retrieved from the Scholarship. (http://hdl.handle.net/10342/4003.)

    Display/Hide MLA, Chicago and APA citation formats.

    MLA:
    Duffy, Brian. Solvent and Solubility Effects on Quinone Ratios. Master's Thesis. East Carolina University, January 2012. The Scholarship. http://hdl.handle.net/10342/4003. August 07, 2022.
    Chicago:
    Duffy, Brian, “Solvent and Solubility Effects on Quinone Ratios” (Master's Thesis., East Carolina University, January 2012).
    AMA:
    Duffy, Brian. Solvent and Solubility Effects on Quinone Ratios [Master's Thesis]. Greenville, NC: East Carolina University; January 2012.
    Collections
    • Chemistry
    • Master's Theses
    Publisher
    East Carolina University

    xmlui.ArtifactBrowser.ItemViewer.elsevier_entitlement

    East Carolina University has created ScholarShip, a digital archive for the scholarly output of the ECU community.

    • About
    • Contact Us
    • Send Feedback