Clogging information flow in ALS
Joseph W. Paul III; Aaron D. Gitler
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating neurodegenerative disorder that causes a progressive loss of motor neurons, leading to paralysis and death typically within 2 to 5 years of onset. There are no cures and few treatments. ALS shares some genetic and pathological overlap with another neurodegenerative disease, frontotemporal dementia (FTD), which causes changes to personality and language. Mutations in the gene called chromosome 9 open reading frame 72 (C9orf72) are the most common genetic cause of both ALS and FTD. This is the author’s version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. The definitive version was published in Science on [Volume 345 on 5 September 2014], DOI: 10.1126/science.1259461.
Joseph W. Paul III, & Aaron D. Gitler. (September 2014). Clogging information flow in ALS. Science, 345(6201), 1118- 1119. Retrieved from http://hdl.handle.net/10342/4589
Joseph W. Paul III, and Aaron D. Gitler. "Clogging information flow in ALS". Science. 345:6201. (1118-1119), September 2014. September 21, 2023. http://hdl.handle.net/10342/4589.
Joseph W. Paul III and Aaron D. Gitler, "Clogging information flow in ALS," Science 345, no. 6201 (September 2014), http://hdl.handle.net/10342/4589 (accessed September 21, 2023).
Joseph W. Paul III, Aaron D. Gitler. Clogging information flow in ALS. Science. September 2014; 345(6201): 1118-1119. http://hdl.handle.net/10342/4589. Accessed September 21, 2023.