Composition, kit and method for treatment of disorders associated withbronchoconstriction and lung inflammation

Abstract

A method of reducing bronchoconstriction in a subject in need of suchtreatment is disclosed. The method comprises administering to the subject an Antisenseoligonucleotide molecule directed against the A.sub.1 or A.sub.3 adenosine receptor in anamount effective to reduce bronchoconstriction. The method is useful for treating patientsafflicted with asthma. Pharmaceutical formulations are also disclosed.