Browsing Microbiology and Immunology by Author "Muller, Uwe R."
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Effect of in vitro transcription on cruciform stability.
Morales, Nydia M.; Cobourn, Scott D.; Muller, Uwe R. (East Carolina University, 1990-05-11)We have investigated the effect of in vitro transcription on cruciform stability. Replicative form DNA of 4X174 strain ins6240, containing a 48 bp synthetic palindrome in the J-F intercistronic region, was supercoiled in ... -
Effects of palindromes on in vivo DNA replication and mutagenesis in bacteriophage phi X174 RF DNA.
Muller, Uwe R.; Perkins, Barbara K.; Williams, W. Lee (East Carolina University, 1988-11-25)Bacteriophage IX174 mutants with insertions of palindromic DNA sequences are rapidly outgrown by competing wild-type phage (Muller & Turnage, J. Mol. Biol. 189: 285). The basis for this defect was investigated and found ...