Browsing Microbiology and Immunology by Author "Pearson, James P."

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  • Inhibition of Quorum Sensing by a Pseudomonas aeruginosa dksA Homologue 

    Branny, Pavel; Pearson, James P.; Pesci, Everett C.; Kohler, Thilo; Iglewski, Barbara H.; Van Delden, Christian (East Carolina University, 2001-03)
    The Pseudomonas aeruginosa las (lasR-lasI) and rhl (rhlR-rhlI) quorum-sensing systems regulate the expression of several virulence factors, including elastase and rhamnolipid. P. aeruginosa strain PR1-E4 is a lasR deletion ...

  • Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa 

    Pesci, Everett C.; Milbank, Jared B. J.; Pearson, James P.; McKnight, Susan L.; Kende, Andrew S.; Greenberg, E. Peter; Iglewski, Barbara H. (East Carolina University, 1999-09-28)
    Numerous species of bacteria use an elegant regulatory mechanism known as quorum sensing to control the expression of specific genes in a cell-density dependent manner. In Gram-negative bacteria, quorum sensing ...