Browsing Microbiology and Immunology by Author "Roper, Rachel L."
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Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments
Brodie, Ryan; Smith, Alex J.; Roper, Rachel L.; Tcherepanov, Vasily; Upton, Chris (East Carolina University, 2004-07-14)Background: With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than gene content because two strains of an ... -
Characterization of the Vaccinia Virus A35R Protein and Its Role in Virulence
Roper, Rachel L. (East Carolina University, 2006-01)The vaccinia virus A35R gene is highly conserved among poxviruses and encodes a previously uncharacterized hydrophobic acidic protein. Western blotting with anti-A35R peptide antibodies indicated that the protein is ... -
Murine mesothelin: characterization, expression, and inhibition of tumor growth in a murine model of pancreatic cancer
Zervos, Emmanuel; Agle, Steven C.; Freistaedter, Andrew G.; Jones, Gwendolyn J. B.; Roper, Rachel L. (2016-03)Background Mesothelin has attracted much interest as a tumor specific antigen; it has been reported to promote tumor development and to be a good target for cancer treatment. Most studies to date have used human mesothelin ...