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Function and regulation of the polysaccharide utilization locus, don, in the gut symbiont bacteroides fragilis
(East Carolina University, 2014)
Bacteroides fragilis is the most common anaerobe isolated from clinical infections and in this report we demonstrate a novel feature of the species that is critical to their success as an opportunistic pathogen. Among the ...
Layered regulation of a pathway capable of altering quinolone production in Pseudomonas aeruginosa
(East Carolina University, 2014)
Pseudomonas aeruginosa is a gram negative opportunistic pathogen which commonly infects hospitalized patients and those afflicted with cystic fibrosis. P. aeruginosa communicates intercellularly via a system of small ...
The iron response regulator Irr controls iron homoeostasis in Brucella
(East Carolina University, 2014)
Members of the genus Brucella are small, Gram-negative intracellular bacterial pathogens that are capable of infecting a wide range of mammalian hosts including humans. Brucella primarily reside inside of host macrophages. ...