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    Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report

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    Author
    Mendez, Carlos E.; Tanenberg, Robert J.; Pories, Walter J.
    Abstract
    Roux-en-Y gastric bypass surgery (RYGB) reverses type 2 diabetes (DM2) in approximately 83% of patients with morbid or severe obesity. This procedure has been performed in small numbers of severely obese patients with type 1 diabetes (DM1), but the impact on glycemic control and insulin requirement in this population has not been widely described. We report three patients with DM1 and severe obesity that underwent RYGB. Weight, glycemic control, and insulin requirements before and one year after the procedure were compared. Significant weight loss was achieved by all three patients but insulin requirements decreased in only 2 patients. In contrast, glycemic control (A1C) remained suboptimal in all three patients up to one year after the surgery. These findings suggest that RYGB leads to important weight loss and positively affects insulin sensitivity. However, reaching optimal glycemic control in patients with DM1 diabetes remains challenging due to persisting insulin deficiency.
    URI
    http://hdl.handle.net/10342/5395
    Subject
     Roux-en-Y; diabetes; gastric bypass; insulin; obesity 
    Date
    2010
    Citation:
    APA:
    Mendez, Carlos E., & Tanenberg, Robert J., & Pories, Walter J.. (January 2010). Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report. Diabetes, metabolic syndrome and obesity : targets and therapy, 3(), 281- 283. Retrieved from http://hdl.handle.net/10342/5395

    Display/Hide MLA, Chicago and APA citation formats.

    MLA:
    Mendez, Carlos E., and Tanenberg, Robert J., and Pories, Walter J.. "Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report". Diabetes, metabolic syndrome and obesity : targets and therapy. 3:. (281-283), January 2010. September 22, 2023. http://hdl.handle.net/10342/5395.
    Chicago:
    Mendez, Carlos E. and Tanenberg, Robert J. and Pories, Walter J., "Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report," Diabetes, metabolic syndrome and obesity : targets and therapy 3, no. (January 2010), http://hdl.handle.net/10342/5395 (accessed September 22, 2023).
    AMA:
    Mendez, Carlos E., Tanenberg, Robert J., Pories, Walter J.. Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report. Diabetes, metabolic syndrome and obesity : targets and therapy. January 2010; 3(): 281-283. http://hdl.handle.net/10342/5395. Accessed September 22, 2023.
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