• Find People
  • Campus Map
  • PiratePort
  • A-Z
    • About
    • Submit
    • Browse
    • Login
    View Item 
    •   ScholarShip Home
    • Academic Affairs
    • Thomas Harriot College of Arts and Sciences
    • Biology
    • View Item
    •   ScholarShip Home
    • Academic Affairs
    • Thomas Harriot College of Arts and Sciences
    • Biology
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of The ScholarShipCommunities & CollectionsDateAuthorsTitlesSubjectsTypeDate SubmittedThis CollectionDateAuthorsTitlesSubjectsTypeDate Submitted

    My Account

    Login

    Statistics

    View Google Analytics Statistics

    Evidence for acquisition of virulence effectors in pathogenic chytrids

    Thumbnail
    View/ Open
    1471-2148-11-195.PMC3161006.pdf (594.4Kb)

    Show full item record
    
    Author
    Sun, Guiling; Yang, Zefeng; Kosch, Tiffany A.; Summers, Kyle; Huang, Jinling
    Abstract
    Background The decline in amphibian populations across the world is frequently linked to the infection of the chytrid fungus Batrachochytrium dendrobatidis (Bd). This is particularly perplexing because Bd was only recently discovered in 1999 and no chytrid fungus had previously been identified as a vertebrate pathogen. Results In this study, we show that two large families of known virulence effector genes, crinkler (CRN) proteins and serine peptidases, were acquired by Bd from oomycete pathogens and bacteria, respectively. These two families have been duplicated after their acquisition by Bd. Additional selection analyses indicate that both families evolved under strong positive selection, suggesting that they are involved in the adaptation of Bd to its hosts. Conclusions We propose that the acquisition of virulence effectors, in combination with habitat disruption and climate change, may have driven the Bd epidemics and the decline in amphibian populations. This finding provides a starting point for biochemical investigations of chytridiomycosis.
    URI
    http://hdl.handle.net/10342/5485
    Date
    2011
    Citation:
    APA:
    Sun, Guiling, & Yang, Zefeng, & Kosch, Tiffany A., & Summers, Kyle, & Huang, Jinling. (January 2011). Evidence for acquisition of virulence effectors in pathogenic chytrids. BMC Evolutionary Biology, (195-195. Retrieved from http://hdl.handle.net/10342/5485

    Display/Hide MLA, Chicago and APA citation formats.

    MLA:
    Sun, Guiling, and Yang, Zefeng, and Kosch, Tiffany A., and Summers, Kyle, and Huang, Jinling. "Evidence for acquisition of virulence effectors in pathogenic chytrids". BMC Evolutionary Biology. . (195-195.), January 2011. March 03, 2021. http://hdl.handle.net/10342/5485.
    Chicago:
    Sun, Guiling and Yang, Zefeng and Kosch, Tiffany A. and Summers, Kyle and Huang, Jinling, "Evidence for acquisition of virulence effectors in pathogenic chytrids," BMC Evolutionary Biology 11, no. (January 2011), http://hdl.handle.net/10342/5485 (accessed March 03, 2021).
    AMA:
    Sun, Guiling, Yang, Zefeng, Kosch, Tiffany A., Summers, Kyle, Huang, Jinling. Evidence for acquisition of virulence effectors in pathogenic chytrids. BMC Evolutionary Biology. January 2011; 11() 195-195. http://hdl.handle.net/10342/5485. Accessed March 03, 2021.
    Collections
    • Biology

    xmlui.ArtifactBrowser.ItemViewer.elsevier_entitlement

    East Carolina University has created ScholarShip, a digital archive for the scholarly output of the ECU community.

    • About
    • Contact Us
    • Send Feedback