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    Species-Specific Expansion and Molecular Evolution of the 3-hydroxy-3-methylglutaryl Coenzyme A Reductase (HMGR) Gene Family in Plants

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    Author
    Li, Wei; Liu, Wei; Wei, Hengling; He, Qiuling; Chen, Jinhong; Zhang, Baohong; Zhu, Shuijin
    Abstract
    Kazakh dandelion (Taraxacum kok-saghyz, Tk) is a rubber-producing plant currently being investigated as a source of natural rubber for industrial applications. Like many other isoprenoids, rubber is a downstream product of the mevalonate pathway. The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) enzyme catalyzes the conversion of 3-hydroxy-3-methylglutaryl-CoA to mevalonic acid, a key regulatory step in the MVA pathway. Such regulated steps provide targets for increases in isoprenoid and rubber contents via genetic engineering to increase enzyme activities. In this study, we identify a TkHMGR1 gene that is highly expressed in the roots of Kazakh dandelion, the main tissue where rubber is synthesized and stored. This finding paves the way for further molecular and genetic studies of the TkHMGR1 gene, and its role in rubber biosynthesis in Tk and other rubber-producing plants.
    URI
    http://hdl.handle.net/10342/5498
    Subject
     Quantitative Polymerase Chain Reaction; Gene Expression; Root; Taraxacum kok-saghyz; 3-Hydroxy-3-Methylglutaryl-CoA Reductase 
    Date
    2014
    Citation:
    APA:
    Li, Wei, & Liu, Wei, & Wei, Hengling, & He, Qiuling, & Chen, Jinhong, & Zhang, Baohong, & Zhu, Shuijin. (January 2014). Species-Specific Expansion and Molecular Evolution of the 3-hydroxy-3-methylglutaryl Coenzyme A Reductase (HMGR) Gene Family in Plants. PLoS ONE, (9:4), p.1-10. Retrieved from http://hdl.handle.net/10342/5498

    Display/Hide MLA, Chicago and APA citation formats.

    MLA:
    Li, Wei, and Liu, Wei, and Wei, Hengling, and He, Qiuling, and Chen, Jinhong, and Zhang, Baohong, and Zhu, Shuijin. "Species-Specific Expansion and Molecular Evolution of the 3-hydroxy-3-methylglutaryl Coenzyme A Reductase (HMGR) Gene Family in Plants". PLoS ONE. 9:4. (1-10.), January 2014. August 11, 2022. http://hdl.handle.net/10342/5498.
    Chicago:
    Li, Wei and Liu, Wei and Wei, Hengling and He, Qiuling and Chen, Jinhong and Zhang, Baohong and Zhu, Shuijin, "Species-Specific Expansion and Molecular Evolution of the 3-hydroxy-3-methylglutaryl Coenzyme A Reductase (HMGR) Gene Family in Plants," PLoS ONE 9, no. 4 (January 2014), http://hdl.handle.net/10342/5498 (accessed August 11, 2022).
    AMA:
    Li, Wei, Liu, Wei, Wei, Hengling, He, Qiuling, Chen, Jinhong, Zhang, Baohong, Zhu, Shuijin. Species-Specific Expansion and Molecular Evolution of the 3-hydroxy-3-methylglutaryl Coenzyme A Reductase (HMGR) Gene Family in Plants. PLoS ONE. January 2014; 9(4) 1-10. http://hdl.handle.net/10342/5498. Accessed August 11, 2022.
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