Browsing Thomas Harriot College of Arts and Sciences by Title
Now showing items 1696-1715 of 3432
-
Investigating the Role of CtBP in Colorectal Cancer
(2015-04-29)Recent studies in breast cancer tissue have demonstrated that C-terminal binding protein (CtBP) over-expression induces stem cell-like features and genome instability; whereas CtBP depletion or caloric restriction reverses ... -
Investigating the role of soil legacy effects and community engagement in the management of Lespedeza cuneata, an invasive legume
(East Carolina University, 2020-11-23)Invasive plant species present a growing threat to biodiversity. Many invasive plants are able to recruit microbial symbionts in their novel range and establish plant-soil feedbacks that influence growth and fitness. These ... -
Investigating the role of transcription factor, Trl, during germline development in the Drosophila ovary
(East Carolina University, 2019-07-22)Oogenesis is the process by which an egg develops from undifferentiated cells in the ovary. The Drosophila melanogaster ovary is an assembly line for egg production, making it a great system to investigate initial oocyte ... -
Investigation Into Intermolecular Interactions of Gd3N@C80(OH)n Using Fluorescence Spectroscopy
(2014)The aim of this experiment was to investigate the intermolecular interactions of the endohedral metallofulerene complex in water and various metal cation solutions. These interactions were observed using a methodology ... -
Investigation Into The Scope, Limitations, And Mechanistic Aspects Of A Regioselective Acylation Of Cycloplatinated Complexes
(East Carolina University, 2015)In the reaction of N-isopropyl-N-phenyl-2,2'-bipyridin-6-amine with potassium tetrachloroplatinate, the selective C-H bond activation was complicated by the low selectivity of sp² C-H bond activation in acetonitrile and ... -
Investigation of Molecular Mechanism of Transthyretin Oligomerization Associated with ATTR Amyloidosis
(East Carolina University, 2022-04-27)Transthyretin amyloidosis (ATTR) has classically been diagnosed predominantly post-observation of amyloid fibril deposition on soft tissues within the body, however, recent studies have shown that oligomers which arise ... -
Investigation of possible driving forces on counter-intuitive thermal collapse of intrinsically disordered proteins
(East Carolina University, 2016-08-18)Intrinsically disordered proteins are an emerging class of proteins that contain no secondary or tertiary structure. Through bioinformatics studies it has been predicted that a third of the human proteome consists of ... -
AN INVESTIGATION OF THE TAPHONOMIC EFFECTS OF ANIMAL SCAVENGING
(East Carolina University, 2014)Numerous environmental and human-induced variables that affect decomposition can cloud accurate estimations of the postmortem interval (PMI). For instance, scavenging animals can remove soft tissue and disarticulate and ... -
Investigation of the Zinc binding region of Prothymosin-alpha : A spectroscopic and thermodynamic approach to study metal binding in Intrinsically disordered proteins
(East Carolina University, 2014)The goal of this study is to provide a deeper insight into how metals bind intrinsically disordered proteins (IDPs) by taking zinc binding to prothymosin-alpha as a case study. The involvement of metals in several diseases ... -
Investigations into the Oldest Standing Structure in North Carolina
(East Carolina University, 1/13/16)In 2010, Steven and Linda Lane purchased 304 East Queen Street, Edenton, North Carolina. While renovating the structure they discovered that it was much older than previously thought. The results of a dendrochronology ... -
Ion Traffic Across Cellular Membranes
(East Carolina University, 2010)The cell membrane protects the delicate internal machinery of the cell and hosts a complex transport system for ion exchange with the environment. Energy is continually expended to maintain a transmembrane electrical ... -
Ionian Revolt, Reconsidered
(East Carolina University, 2010)In the scope of historical events recorded by Herodotus, no event has been more pivotal in capturing the relationship between the mainland and Ionian Greeks and their enemy, and at times supporter, Persian Empire than the ... -
IRON ISOTOPE GEOCHEMISTRY OF BULK ROCKS AND Fe-Ti OXIDES FROM THE SKAERGAARD LAYERED MAFIC INTRUSION, SE GREENLAND
(East Carolina University, 2019-07-23)Small, but significant fractionation of Fe isotopes occurs in high-temperature igneous rocks. Despite increasing study, the exact causes of this fractionation are still debated. Therefore, a systematic study of a complete ... -
The Iron Sentinel: U.S.S. MICHIGAN 1844-1949
(1985-11) -
Irredundant and Mixed Ramsey Numbers
(East Carolina University, 2013)The irredundant Ramsey number, s(m,n), is the smallest p such that in every two-coloring of the edges of K[subscript]p using colors red (R) and blue (B), either the blue subgraph contains an m-element irredundant set or ...