Browsing Thomas Harriot College of Arts and Sciences by Title
Now showing items 2495-2514 of 3432
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The Role of eIF4G-1 Isoforms and Live Cell Imaging of IRES-mediated Translation Initiation in Breast Cancer Cells
(East Carolina University, 2012)The development of cancer is a consequence of mutations that lead to dysfunctional cell processes such as unrestrained cell proliferation, resistance to apoptosis, and improper regulation of cell processes such as translation. ... -
The Role of GSK-3[beta] in MCF-7 Breast Cancer Cell Signaling and Drug Resistance
(East Carolina University, 2011)Glycogen synthase kinase- 3beta (GSK-3beta) is well documented to participate in a complex array of critical cellular processes. This versatile protein is involved in numerous signaling pathways that influence metabolism, ... -
The Role of Mitochondrial Biogenesis in Human Mesenchymal Stem Cell Differentiation and Acquisition of a Cardiac Phenotype
(East Carolina University, 2013)Introduction: With an increased understanding of myocardial infarction, human mesenchymal stem cell (hMSC) transplantation therapies have shown promising results as a possible treatment for heart failure. However, little ... -
THE ROLE OF ROYAL POWER IN THE FORMATION OF AN ANGLO-SAXON STATE, CIRCA 400-900 AD
(East Carolina University, 2012)This thesis explores the formation of a state in Anglo-Saxon England from the period of Roman withdrawal from Britain in the early fifth century to the tenth century. It argues that the key factor in the development of the ... -
THE ROLE OF SDF-1[alpha] AS A VASCULOGENIC CHEMOKINE AND ENDOTHELIUM-ASSOCIATED CELL ADHESION MOLECULE FOR THE RECRUITMENT OF BONE MARROW-DERIVED PROGENITOR CELLS TO DEVELOPING TUMORS
(East Carolina University, 2010)Tumor vascularization is an important control point in cancer progression and its inhibition is a promising approach to cancer therapy. Stromal-derived factor-1 alpha (SDF-1 alpha or CXCL12) is a chemoattractant for ... -
The Role of Self-Efficacy and Possible Selves as Related to Personal Goals in an Employee Wellness Program
(East Carolina University, 2011)The aim of the present study was to explore the role of self-efficacy and possible selves in relation to the attainment of personal goals for participants of an employee wellness program. Also investigated was whether any ... -
The Role of Transcription Factors Snail and Slug in Cardiac Myofibroblasts
(East Carolina University, 2014)CCardiac fibrosis is a major facet contributing to cardiac dysfunction following a myocardial infarction. Persistent and excessive collagen deposition via cardiac myofibroblasts is the hallmark of cardiac fibrosis. Cardiac ... -
Root parasitic plant and shoot parasitic plant obtained Brassicaceae-specific genes by horizontal gene transfer
(2014)Background Besides gene duplication and de novo gene generation, horizontal gene transfer (HGT) is another important way of acquiring new genes. HGT may endow the recipients with novel phenotypic traits that are important ... -
Rosie the Riveter and the Kitchen Soldier : Fighting the Second World War from Wilmington, North Carolina
(East Carolina University, 2015)The purpose of this thesis is to examine whether or not traditional gender norms remained standing at the conclusion of World War II in Wilmington, North Carolina. This topic would have been impossible to cover on a ... -
Rubble Along the Road: Determining the Function and Date of Occupation for a Structure on Orton Plantation
(East Carolina University, 2019-05-02)There is little known about the daily lives of the enslaved and tenant farming African Americans who lived in the Lower Cape Fear region of North Carolina during the 19th and early 20th centuries. Even on the larger ... -
Rules of (employee) engagement: A comprehensive model
(East Carolina University, 2016-12-15)The purpose of the study was to examine a comprehensive model of employee engagement that included a diverse set of (1) personal factors, (2) environmental factors, (3) job attitudes, (4) work outcomes and (5) health ... -
RURALITY
(East Carolina University, 2020-06-22)Rurality is a collection of short fiction that seeks to explore the unique lives of characters in rural areas. The stories display the ways in which characters engage moral codes and challenges, while remaining in pursuit ...