Browsing Thomas Harriot College of Arts and Sciences by Title
Now showing items 3148-3167 of 3432
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Thermal stress in artificial cavity-nesting Eastern Bluebirds: killing them with kindness?
(East Carolina University, 2018-05-03)Artificial nest boxes are used to help cavity-nesting species with declining populations that compete for limited nest sites. Proper use of nest boxes has been shown to lower predation rates and ectoparasite loads. However, ... -
Thermodynamic and spectroscopic studies of Cd²⁺ binding to the regulatory domain and full length human cardiac troponin C (HcTnC) : elucidating plausible Cd²⁺ binding sites
(East Carolina University, 2015)Toxic metals such as cadmium (Cd²⁺) have been shown to bind to and interfere with various calcium (Ca²⁺) binding proteins including the regulatory protein cardiac troponin C (cTnC). Recent structural data has shown that ... -
Thermodynamic Investigation into the Binding Properties of Cardiac Troponin (Human and Bovine)
(East Carolina University, 2010)Troponin is an integral protein in the mechanism of muscle contraction. In order to induce cardiac muscle contraction, Ca[superscript]2[superscript]+ must bind to the TnC subunit (calcium binding subunit) of troponin to ... -
Thermodynamic Investigation of Copper Binding to the Amyloid-Beta (A[beta]) Peptide
(East Carolina University, 2010)Alzheimer's disease is a fatal and neurodegenerative disease with as many as 5.3 million Americans living with the disease. One of the characteristic hallmarks of Alzheimer's is the amyloid plaques that build up around the ... -
Thermodynamic Investigations into Copper Binding in the N-Terminal Region of the Prion Protein at Low Copper Loadings
(East Carolina University, 2010)The prion protein (PrP) is a naturally occurring protein found at high levels in central nervous system (CNS). The misfolding of the PrP is responsible for neurodegenerative diseases called transmissible spongioform ... -
Thermodynamic studies of Ca²⁺ binding to human cardiac troponin C
(East Carolina University, 2012)Human Cardiac Troponin C (HcTnC) is an EF hand protein responsible for initiating contraction of the myocardium (heart muscle). The helix-loop-helix motif, characteristic of members of the EF-hand family, allows HcTnC to ... -
"They Would Have a Law of Their Own" : The Discourse on Smuggling at the Old Bailey, 1736-1814
(East Carolina University, 2013)This thesis examines the cases of 136 men tried for smuggling offenses at London's central criminal court during the long eighteenth century. Before the 1770s, the government portrayed smuggling as a crime against the ... -
The Things We Hear in the Nighttime & Other Stories
(East Carolina University, 2015)THE THINGS WE HEAR IN THE NIGHTTIME & OTHER STORIES is a collection of five short stories and five pieces of flash fiction. The writing in the collection focuses on the ever-changing American identity of the 20th and 21st ... -
THREE FACETS OF EMPLOYEE WELLNESS: THE POTENTIAL MODERATING INFLUENCES OF MINDFULNESS, PHYSICAL ACTIVITY, AND VACATION ON SELECT WORKER CHARACTERISTICS
(East Carolina University, 2020-06-22)Workaholism is well-known for the negative effects it has on workers, including poor individual health and an inability to separate oneself from work. Furthermore, a strong positive correlation between workaholism and work ... -
Three Generations, One Future: A Systematic Analysis on Nicotine's Effect across generations in C. elegans.
(East Carolina University, 2013)Tobacco smoking is a worldwide epidemic that is responsible for diseases and death rates that surpass those attributed to a combination of other causes (e.g. cancer, HIV, accidents). A major mediator of tobacco-smoke related ... -
Thrown Voices : A Series of Dramatic Monologues, With a Discussion of the Genre
(East Carolina University, 2010)This thesis examines the complex nature of the poetic genre of the dramatic monologue by providing multiple perspectives on the genre--namely, those of the literary critic and the creative writer. This thesis provides a ...