Browsing Thomas Harriot College of Arts and Sciences by Author "Rudel, David"
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Assaying Environmental Nickel Toxicity Using Model Nematodes
Rudel, David; Douglas, Chandler D.; Huffnagle, Ian M.; Besser, John M.; Ingersoll, Christopher G. (2013)Although nickel exposure results in allergic reactions, respiratory conditions, and cancer in humans and rodents, the ramifications of excess nickel in the environment for animal and human health remain largely undescribed. ... -
Assessing cellular and genomic damage from environmental nickel using a GFP containing strain of Caenorhabditis elegans
Huffnagle, Ian M. (East Carolina University, 2013)Nickel is a naturally found mineral that has become widely used for many electronic devices. As use and subsequent discarding of nickel containing products continues exposure to nickel increases. Nickel can cause external ... -
Complementary Square Wave Voltammetry and Tandem Mass Spectrometry Analysis to Identify and Detect Compensatory Genomic Changes in Nematodes Due to Nickel (II) Exposure
LaFave, Elizabeth R.; Turner, Ryne; Schaaf, Nicholas J.; Hindi, Thekra; Rudel, David; Hvastkovs, Eli G. (2022) -
The effects of environmental nickel toxicity upon survival, growth, reproduction, fecundity, and lifespan of nematodes Caenorhabditis elegans, Pristionchus pacificus, and Caenorhabditis briggsae
Douglas, Chandler D. (East Carolina University, 2012)Nickel (II) is a common component of many natural products and man-made devices. Due to its frequent use in everyday life, relatively large amounts of nickel are being released into the environment. Nickel, however, is a ... -
Elucidating the mechanisms of Nickel as an animal mutagen
Campbell, Halbert Eugene (East Carolina University, 2016-04-28)Nickel is an essential metal for many organisms. Nickel occurs naturally from volcanism and weathering of stone. Recently production of nickel from anthropogenic sources has overtaken natural production. Combustion of ... -
The Evolution of Organ Shape : Distal Tip Cell Migration and Gonadogenesis in Nematodes
Wyatt, Brent (East Carolina University, 2013)Animals display a variety of shapes in nature. The different shape of homologous organs allows them to adopt different functions and therefore, allows animals to live in different ecological niches. However, little is ... -
Identifying compensatory genomic changes due to nickel (Ni2+) exposure: electrochemistry and quantifying DNA damage
Turner, Ryne (East Carolina University, 2020-11-24)Nickel is a toxic heavy metal that has been shown to cause adverse healthconditions in organisms. DNA damage has been observed in nematodes in response to nickel exposure. Nematodes originating from environments with high ... -
Nickel as a mutagen and as an enabler of EMS genotoxicity in Caenorhabditis elegans
Atkinson, John (East Carolina University, 2016-01-15)Nickel is found naturally and vital for survival of some organisms. Nickel occurs as a metal as insoluble compounds and soluble compounds. Nickel exposure has increased due to urbanization from various sources including ...