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Investigation of the Zinc binding region of Prothymosin-alpha : A spectroscopic and thermodynamic approach to study metal binding in Intrinsically disordered proteins
(East Carolina University, 2014)
The goal of this study is to provide a deeper insight into how metals bind intrinsically disordered proteins (IDPs) by taking zinc binding to prothymosin-alpha as a case study. The involvement of metals in several diseases ...
Using Mosquitofish, Gambusia affinis, as Bioindicators for the presence of Endocrine Disrupting Compounds in Greenville's Wastewater Effluent
(2014)
Endocrine disrupting compounds (EDCs) are compounds that arise from an assortment of manufactured sources (plastics, pharmaceuticals, pulp mill waste), which have the potential to interrupt hormone pathways by mimicking ...
Conservation and Expression of SNF2 Proteins in Chondrus crispus
(2014)
The SNF2 families of ATP-dependent helicases are the central catalytic subunits for chromatin remodeling complexes. The most widely studied is the multisubunit SWI/SNF complex, which has been found in plants, yeast, and ...
Fundamental and Applied Studies on Chromatographic Separation of Cold Drugs and Skincare Creams and Extraction of Salvia miltiorrhiza using Subcritical Water
(East Carolina University, 2014)
Subcritical water chromatography (SBWC) and subcritical water extraction (SBWE) are two green techniques that use subcritical water as the sole solvent for separations, thus eliminating the use of toxic and expensive organic ...
Comparison of ZnO nanoparticles and ZnCl₂ induced germ cell apoptosis in Caenorhabditis elegans
(East Carolina University, 2014)
There is inadequate research data available on manufactured ZnO nanoparticles. Manufactured nanoparticles are widely used in various products and production of manufactured nanoparticles is becoming increasingly abundant. ...
Elizabeth I, Visual Icon : A Title Unintended
(East Carolina University, 2014)
This thesis explores Elizabeth I's relationship with her official state portraiture to show that she placed little value in its meaning and authority for political and diplomatic uses. Understanding her personal relationship ...
Maternal input of Striped Bass (Morone saxatilis) : Determining a mother's life history from its progeny in coastal North Carolina
(East Carolina University, 2014)
Otolith studies have become more prevalent in recent years as use has expanded from ageing to examination of migration patterns and fidelity to natal habitats, and more recently examining otoliths for possible maternal ...
The Effects of Moral Self-Reflective Priming on Faking in Personality Testing
(East Carolina University, 2014)
Personality testing has received considerable criticism due to validity coefficients being weakened by intentional response distortion. The current study investigates whether priming an individual with a moral self-reflective ...
"Of my own accord" : Milton's Dialogue with the Rabbis in Samson Agonistes
(East Carolina University, 2014)
This thesis examines rabbinic commentaries on the Samson story and the ways in which Milton appropriates or differs from these interpretations. It considers the critical debate over whether Samson's character and violent ...
Electrochemical Detection of Benzo[a]Pyrene-Induced DNA Damage at TP53 Oligomers : Impact of 5'-Methyl Cytosine and Bioactivation on the Genotoxicity Process
(East Carolina University, 2014)
DNA houses the blueprint that dictates how an organism will develop. However, DNA features numerous reactive sites that can be attacked by chemicals and radiation, resulting in DNA damage and possibly mutations. Chemical ...