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protaTETHER – a method for the incorporation of variable linkers in protein fusions reveals impacts of linker flexibility in a PKAc‐GFP fusion protein
(2018-03-14)
Protein fusions are of fundamental importance in the study of cellular biology and the elucidation of cell signaling pathways, and the importance of linkers for the proper function of protein fusions is well documented in ...
Role of Blood Cytokine Levels and Adiposity in Myocardial Infarction Recurrence
(2018-05)
Risk factors for myocardial infarction (MI) are important as cardiovascular disease is the leading cause of death. In fact, approximately one third of adults having an MI will have another in six years. The purpose of this ...
Prisons and Pollutant Plumes: A Spatial Analysis of LULU Coexistence
(East Carolina University, 2018-07-20)
Prison facilities and other locally unwanted land uses (LULUs) lead to a number of health, environmental, and socio-economic impacts on the local community. Prison facilities and other LULUs tend to be sited in locations ...
A Biopsychosocial Examination of Transcatheter Aortic Valve Replacement Health Outcomes
(East Carolina University, 2015)
Cardiovascular disease (CVD) is the leading cause of death in the world accounting for 17.3 million deaths annually. Transcatheter aortic valve replacement (TAVR) was developed 13 years ago to treat people suffering from ...
Understanding Trauma Reactions in Implantable Cardioverter Defibrillator Patients and Piloting a Brief Web-based Trauma Intervention Protocol Study (ICD-TIPS)
(East Carolina University, 2014)
Background: Approximately 20% of patients with an implantable cardioverter defibrillator (ICD), a medical device that prevents sudden cardiac arrest (SCA) and mortality, score above a clinical cutoff on a screening measure ...
Geometry and construction history of a complex intrusive center in the shallow crust, Mount Pennell, Henry Mountains, Utah
(East Carolina University, 2014)
Large igneous intrusions grow from incremental emplacement of relatively small batches of magma. The Henry Mountains have been the subject of investigation because multiple, well-exposed intrusive centers are present on ...
Assessing the shallow groundwater system as a potential factor in generating storm-water runoff on a North Carolina barrier island
(East Carolina University, 2013)
The town of Emerald Isle, located in North Carolina's Outer Banks, experiences significant storm-water runoff and flooding problems during the fall and winter months. The topography of the island influences drainage patterns ...
Dietary Reconstruction Of Urban Inhabitants Of The 1St Century AD Petra
(East Carolina University, 2015)
Petra, an ancient city located in southern Jordan, is a UNESCO World Heritage site known for its architecturally grand buildings and tombs carved into sandstone bedrock. The establishment of Petra as the capital of the ...
Evaluating The Essential Functions Of The Replication Factor Mcm10 In Drosophila Melanogaster
(East Carolina University, 2015)
Often referred to as miraculous, life as we know depends not upon miracles but on a series of highly orchestrated and regulated biochemical processes collectively known as the cell cycle. It is through these series of ...
Antiseptic Humor : Using Comedy To Confront Realities And Refute Stereotypes In The Works Of Sherman Alexie
(East Carolina University, 2015)
Sherman Alexie, a Native American author of poems, novels, plays, and film uses humor to expose and to explore lingering cultural stereotypes affecting people of Native American ancestry. These stereotypes often conflict ...