Browsing Biology by Type"Master's Thesis"
Now showing items 1-20 of 221
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A Candidate Gene Study: Finding Associations between Recurrent Stroke and Genetic Variants of Five Folate-Mediated One Carbon Metabolism Pathway Genes
(East Carolina University, 2019-04-25)Stroke is the second leading cause of death in the world and fifth in the United States. Both in the United States and worldwide, stroke is the leading cause of disability. Stroke is a cerebrovascular event which results ... -
A metabolomics approach to understanding recurrent stroke risk in African Americans
(East Carolina University, 2019-07-02)Stroke is a significant health burden, as the fifth leading cause of death and the number one cause of serious, long term disability in the United States. Each year 795,000 individuals suffer a stroke; of which 185,000 ... -
A QUALITATIVE STUDY OF MICROBES IN SERPENTINITE-HOSTED SUBSURFACE ENVIRONMENTS
(East Carolina University, 1/13/16)Over the last two decades, serpentinizing environments have been studied with regards to the biogeochemistry of these habitats, but significantly less is known about the microbiology within these environments. Serpentinization ... -
The Acquisition of a Plastid by Haptophytes, Cryptophytes, and Photosynthetic Heterokonts
(East Carolina University, 2014)Red algae and green plants are known to have obtained their photosynthetic organelles, or plastids, through the endosymbiotic adoption of cyanobacteria. It is still widely debated as to how other eukaryotic alga such as ... -
Activation of GPR4 by acidosis inhibits tumor cell migration, invasion and metastasis.
(East Carolina University, 2011)Melanoma and Prostate Cancer are two of the most diagnosed forms of cancer in the United States. The ability to metastasize and colonize in a distant location is one of the most devastating hallmarks of cancer as modes ... -
ADAMTS9 IS NECESSARY FOR THE SEXUAL DEVELOPMENT OF FEMALE ZEBRAFISH
(East Carolina University, 2018-12-10)The ovary is a unique organ as it must cyclically alter its structure to accommodate the growth, development, and release of oocytes. The processes of oogenesis and ovulation requires structural modifications made to the ... -
An exploration of inter-clutch variability and eggshell patterning in two species of rail
(East Carolina University, 2021-05-10)The avian egg has long fascinated researchers with its diverse colors, patterns, and shapes. Variation within and between species provides opportunities to address the question of why eggs are pigmented the way they are. ... -
An investigation of alkaloid sequestration by the poison frog Dendrobates auratus when fed the fire ant Solenopsis invicta
(East Carolina University, 1/13/16)Poison frogs are known for their bright coloration, parental care, and defensive toxins. Over 850 different alkaloids have been discovered in the skin of poison frogs. The alkaloid defenses are acquired from a specialized ... -
Analysis of a 41-year data set : Environmental influences on the fish assemblages of Albemarle Sound, North Carolina
(East Carolina University, 2014)North Carolina both historically and currently maintains one of the most productive fishery resource basins in the nation. However, fish stocks are spatially and temporally variable in abundance and distribution in estuarine ... -
Analysis of Complex DNA Damage Associated with Tumor Growth
(East Carolina University, 2012)The innate response of a fully functioning immune system's ability to recognize and react to the growth of a tumor by releasing reactive oxygen species (ROS) may lead to chronic inflammation in many cases. This chronic ... -
Analysis of Myopodin in Hela Cervical Carcinoma Cells
(East Carolina University, 2014)Synaptopodin-2 is a proline-rich, actin-binding protein that exists in many isoforms. Due to its large proline content, synaptopodin-2 exists in a naturally unfolded state and possesses the characteristics of a hub protein. ... -
Analysis of scn5Laa and scn5Lab Gene Function in Danio rerio (Zebrafish) Heart Development through TALENs/CRISPR-CAS9-mediated Gene Knockout
(East Carolina University, 2015)Research in our laboratory is focused on understanding the molecular developmental genetic effects of crude oil exposure on vertebrate embryogenesis. Our research has demonstrated that exposure of zebrafish embryos to ... -
Analysis of the hex regulon in Pseudomonas aeruginosa
(East Carolina University, 2012)Pseudomonas aeruginosa is an opportunistic pathogen whose defense mechanisms include biofilm production through carbohydrate metabolism. The activity of the enzymes in the hex regulon are required for catabolism of glucose ... -
Anti-Cancer Activity of Cucurbitacin IIa
(East Carolina University, 2012)Cancer is a debilitating disease resulting from uncontrolled proliferation. One major treatment strategy for cancer is the application of chemotherapeutic drugs which kill cancer cells. Cucurbitacins are a new family ... -
Are All Parasitic Infections Created Equal? An Examination of Differential Infection Effects and Responses in Native and Non-Native Hosts
(East Carolina University, 2018-12-10)Interactions between native and introduced species are complex, multifaceted, and can have cascading effects throughout an ecosystem. While scientists have taken great strides to understand how these dynamics change with ... -
Assessing cellular and genomic damage from environmental nickel using a GFP containing strain of Caenorhabditis elegans
(East Carolina University, 2013)Nickel is a naturally found mineral that has become widely used for many electronic devices. As use and subsequent discarding of nickel containing products continues exposure to nickel increases. Nickel can cause external ... -
Assessing The Monophyly Of Red Algae And Green Plants Via Core Conserved Informational Genes
(East Carolina University, 2015)For well over a century the existence of a monophyletic relationship between red algae and green plants has been debated. Many scholars have sought to address this issue, however, a consistent solution to the problem has ... -
Behavioral syndromes and their effect on dispersal in Notonecta irrorata
(East Carolina University, 2018-04-23)Dispersal is an important life-history characteristic for many organisms, including in the genus of back-swimming insect Notonecta. The propensity to disperse is a behavior that might be affected by an individual's other ... -
Bioenergetics and Trophic Impacts of Invasive Indo-Pacific Lionfish
(East Carolina University, 2010)Indo-Pacific lionfish, Pterois volitans and Pterois miles, are non-native marine fish with established populations in the western North Atlantic Ocean and Caribbean Sea. Rapid population growth threatens native fish ... -
Biogeographic Characterization of Fishes from Intertidal Sandflats in Pamlico River, North Carolina
(East Carolina University, 2012)The spatial and temporal changes in fish community structure in Pamlico River, North Carolina were analyzed. Salinity and temperature are important water quality parameters influencing fish community structure in estuaries. ...