Browsing Biology by Title
Now showing items 1081-1100 of 1310
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Targeting aberrant signaling in the EGFR1/HER2/PI3K/PTEN/Akt/mTORC1/GSK-3 pathway : Novel therapeutic interventions in breast cancer
(East Carolina University, 2015)Breast cancer is attributed to being the second most deadly cancer in American women. Approximately 1 in 8 women will be diagnosed with breast cancer during her lifetime, and prognosis is dependent upon the genetic make-up ... -
TEMPERATURE, RESOURCE INPUT, AND STANDING GENETIC VARIATION AFFECT PREDATOR RESPONSES OF PHYSA ACUTA
(East Carolina University, 2019-04-26)In urban areas, features such as high percentages of impervious ground cover, patchiness, and storm water runoff can lead to increases in temperature and external nutrient input into aquatic systems. Such factors can lead ... -
TEMPORAL AND SPATIAL GRADIENTS IN PHYTOPLANKTON PIGMENTS IN THE TAR-PAMLICO RIVER ESTUARY
(East Carolina University, 2016-04-28)Phytoplankton form the base of most aquatic food webs, and their biomass and the composition of their communities directly impact upper trophic levels. Phytoplankton chlorophyll a concentrations in aquatic environments ... -
TGF-β1-directed Smad3 stimulates proliferation and alters morphology of rat primary vascular smooth muscle cells
(East Carolina University, 2017-05-05)With cardiovascular disease (CVD) being the leading cause of morbidity and death in the United States and worldwide (2, 28), studying the mechanisms of these pathologies is imperative. Recent studies have shown that a ... -
THE ANTAGONISTIC AND MUTUALISTIC PLANT-INSECT INTERACTIONS OF PITCHER’S THISTLE (CIRSIUM PITCHERI [TORR. EX EAT.] TORR. & A. GRAY, ASTERACEAE), A FEDERALLY THREATENED GREAT LAKES DUNE AND COBBLE SHORE ENDEMIC PLANT
(East Carolina University, 2016-05-04)Biological control is one of the tools used for integrated pest management of invasive plant species but it is not without risks to native plants. I researched the non-target impacts of the biological control agent, the ... -
The CDF-type metal efflux protein EmfA is essential for Brucella abortus 2308 resistance to manganese toxicity and is a critical virulence determinant in experimentally-infected mice
(East Carolina University, 2019-05-13)Divalent cationic metals are important trace nutrients for all bacteria because metals serve as cofactors for proteins involved in numerous cellular functions. Despite the fact that metals play an essential role in bacterial ... -
The Direct and Indirect Impact of Sucralose on Immune Function
(East Carolina University, 2017-12-18)1, 6-dichloro-1, 6- dideoxy-[beta]-D-fructofuranosyl-4-chloro-4-deoxy -[alpha]-D-galactopyranoside, or Sucralose, is a highly popular NAS (Non-caloric artificial sweetener) used by millions across the globe for sweetening ...