Now showing items 541-560 of 1310

  • A Functional Analysis of microRNAs in Nicotiana tabacum 

    Burklew, Caitlin E. (East Carolina University, 2012)
    MicroRNAs (miRNAs) are a newly discovered class of endogenous post-transcriptional gene regulators that are typically 20-22 nucleotides in length that do not code for proteins. MiRNAs regulate gene expression by either ...
  • Functional Unit of the RNA Polymerase II C-Terminal Domain Lies within Heptapeptide Pairs  

    Stiller, John W.; Cook, Matthew S. (East Carolina University, 2004-06)
    Unlike all other RNA polymerases, the largest subunit (RPB1) of eukaryotic DNA-dependent RNA polymerase II (RNAP II) has a C-terminal domain (CTD) comprising tandemly repeated heptapeptides with the consensus sequence ...
  • FUNCTIONS OF G-PROTEIN COUPLED ESTROGEN RECEPTOR (GPER) IN FEMALE ZEBRAFISH REPRODUCTION 

    Williams, Marcus Jermaul Jawanza (East Carolina University, 2019-11-27)
    Abstract Steroid hormones such as estrogen depend on receptors like Estrogen Receptor alpha (ERα) and Estrogen Receptor (ERβ) to mediate their slow “genomic” functions, and G-Protein coupled Estrogen Receptor (GPER) to ...
  • Fungicide Difenoconazole Induced Biochemical and Developmental Toxicity in Wheat (Triticum Aestivum L.) 

    Zhang, Baohong; Liu, Runqiang; Jingchong Li, Jingchong; Zhang, Lei; Feng, Ta; Zhang, Zhiyong (2021-10-26)
  • The Fur-like regulator Mur controls the expression of the gene encoding the manganese transporter MntH in Brucella abortus 2308 in response to manganese availability 

    Menscher, Evan A. (East Carolina University, 2011)
    Brucella abortus is a Gram-negative, [alpha]-proteobacterium that causes bovine brucellosis, a prevalent zoonotic disease in many areas of the world. Brucella abortus is an intracellular pathogen that survives and ...
  • FUSTr: A Tool to Find Gene Families Under Selection in Transcriptomes 

    Brewer, Michael S.; Cole, T. Jeffrey (2018-01-17)
  • Gamma Protocadherin Expression in the Embryonic Chick Nervous System 

    Cronin, Kenneth D.; Capehart, Anthony A. (East Carolina University, 2007)
    Protocadherin gamma (pcdh-gamma) family expression was examined in the embryonic chick central nervous system by in situ hybridization. Transcripts were visualized in discrete regions of fore-, mid-, and hindbrain at stages ...
  • Gene Expression and the Evolution of Reduced Sexual Dimorphism in a Threespine Stickleback Color Trait 

    Newsome, William Burns (East Carolina University, 2017-01-03)
    Elucidating the processes and mechanisms responsible for sexual dimorphism has been a central task for evolutionary biologists since Darwin first proposed the concept of sexual selection. However, our understanding of the ...
  • Gene Expression Divergence Between Zebra Finch (Taeniopygia Guttata) Subspecies And Gene Regulation In Hybrids 

    Davidson, John H. (East Carolina University, 2015)
    Since the publication of Mayr's Systematics and the Origin of Species, birds have been important model organisms for studies regarding evolutionary processes such as sexual selection and speciation. In this study, I will ...
  • Gene Expression in Male and Female Stickleback from Populations with Convergent and Divergent Throat Coloration 

    McKinnon, Jeffrey S.; Newsome, William Burns; Balakrishnan, Christopher N. (2022)
  • Gene Regulatory Evolution During Speciation in a Songbird 

    Balakrishnan, Christopher N. (2016-05-01)
  • Genetic Architecture of Conspicuous Red Ornaments in Female Threespine Stickleback 

    Yong, Lengxob; Peichel, Catherine L.; McKinnon, Jeffrey S. (2015-12)
    Explaining the presence of conspicuous female ornaments that take the form of male-typical traits has been a longstanding challenge in evolutionary biology. Such female ornaments have been proposed to evolve via both ...
  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function 

    Pattaro, Cristian; Teumer, Alexander; Gorski, Mathias; Chu, Audrey Y.; Li, Man; Mijatovic, Vladan; Garnaas, Maija; Tin, Adrienne; Sorice, Rossella; Li, Yong; Taliun, Daniel; Olden, Matthias; Foster, Meredith; Yang, Qiong; Chen, Ming-Huei; Pers, Tune H.; Johnson, Andrew D.; Ko, Yi-An; Fuchsberger, Christian; Tayo, Bamidele; Nalls, Michael A.; Feitosa, Mary F.; Isaacs, Aaron; Dehghan, Abbas; d'Adamo, Pio; Adeyemo, Adebowale; Dieffenbach, Aida Karina; Zonderman, Alan B.; Nolte, Ilja M.; van der Most, Peter J.; Wright, Alan F.; Shuldiner, Alan R.; Morrison, Alanna C.; Hofman, Albert; Smith, Albert V.; Dreisbach, Albert W.; Franke, Andre; Uitterlinden, Andre G.; Metspalu, Andres; Tonjes, Anke; Lupo, Antonio; Robino, Antonietta; Johansson, Åsa; Demirkan, Ayse; Kollerits, Barbara; Freedman, Barry I.; Ponte, Belen; Oostra, Ben A.; Paulweber, Bernhard; Krämer, Bernhard K.; Mitchell, Braxton D.; Buckley, Brendan M.; Peralta, Carmen A.; Hayward, Caroline; Helmer, Catherine; Rotimi, Charles N.; Shaffer, Christian M.; Müller, Christian; Sala, Cinzia; van Duijn, Cornelia M.; Saint-Pierre, Aude; Ackermann, Daniel; Shriner, Daniel; Ruggiero, Daniela; Toniolo, Daniela; Lu, Yingchang; Cusi, Daniele; Czamara, Darina; Ellinghaus, David; Siscovick, David S.; Ruderfer, Douglas; Gieger, Christian; Grallert, Harald; Rochtchina, Elena; Atkinson, Elizabeth J.; Holliday, Elizabeth G.; Boerwinkle, Eric; Salvi, Erika; Bottinger, Erwin P.; Murgia, Federico; Rivadeneira, Fernando; Ernst, Florian; Kronenberg, Florian; Hu, Frank B.; Navis, Gerjan J.; Curhan, Gary C.; Ehret, George B.; Homuth, Georg; Coassin, Stefan; Thun, Gian-Andri; Pistis, Giorgio; Gambaro, Giovanni; Malerba, Giovanni; Montgomery, Grant W.; Eiriksdottir, Gudny; Jacobs, Gunnar; Li, Guo; Wichmann, H-Erich; Campbell, Harry; Schmidt, Helena; Wallaschofski, Henri; Völzke, Henry; Brenner, Hermann; Kroemer, Heyo K.; Kramer, Holly; Lin, Honghuang; Leach, I. Mateo; Ford, Ian; Guessous, Idris; Rudan, Igor; Prokopenko, Inga; Borecki, Ingrid B.; Heid, Iris M.; Kolcic, Ivana; Persico, Ivana; Jukema, J. Wouter; Wilson, James F.; Felix, Janine F.; Divers, Jasmin; Lambert, Jean-Charles; Stafford, Jeanette M.; Gaspoz, Jean-Michel; Smith, Jennifer A.; Faul, Jessica D.; Wang, Jie Jin; Ding, Jingzhong; Hirschhorn, Joel N.; Attia, John; Whitfield, John B.; Chalmers, John; Viikari, Jorma; Coresh, Josef; Denny, Joshua C.; Karjalainen, Juha; Fernandes, Jyotika K.; Endlich, Karlhans; Butterbach, Katja; Keene, Keith L.; Lohman, Kurt; Portas, Laura; Launer, Lenore J.; Lyytikäinen, Leo-Pekka; Yengo, Loic; Franke, Lude; Ferrucci, Luigi; Rose, Lynda M.; Kedenko, Lyudmyla; Rao, Madhumathi; Struchalin, Maksim; Kleber, Marcus E.; Cavalieri, Margherita; Haun, Margot; Cornelis, Marilyn C.; Ciullo, Marina; Pirastu, Mario; de Andrade, Mariza; McEvoy, Mark A.; Woodward, Mark; Adam, Martin; Cocca, Massimiliano; Nauck, Matthias; Imboden, Medea; Waldenberger, Melanie; Pruijm, Menno; Metzger, Marie; Stumvoll, Michael; Evans, Michele K.; Sale, Michele M.; Kähönen, Mika; Boban, Mladen; Bochud, Murielle; Rheinberger, Myriam; Verweij, Niek; Bouatia-Naji, Nabila; Martin, Nicholas G.; Hastie, Nick; Probst-Hensch, Nicole; Soranzo, Nicole; Devuyst, Olivier; Raitakari, Olli; Gottesman, Omri; Franco, Oscar H.; Polasek, Ozren; Gasparini, Paolo; Munroe, Patricia B.; Ridker, Paul M.; Mitchell, Paul; Muntner, Paul; Meisinger, Christa; Smit, Johannes H.; Kovacs, Peter; Wild, Philipp S.; Froguel, Philippe; Rettig, Rainer; Mägi, Reedik; Biffar, Reiner; Schmidt, Reinhold; Middelberg, Rita P. S.; Carroll, Robert J.; Penninx, Brenda W.; Scott, Rodney J.; Katz, Ronit; Sedaghat, Sanaz; Wild, Sarah H.; Kardia, Sharon L. R.; Ulivi, Sheila; Hwang, Shih-Jen; Enroth, Stefan; Kloiber, Stefan; Trompet, Stella; Stengel, Benedicte; Hancock, Stephen J.; Turner, Stephen T.; Rosas, Sylvia E.; Stracke, Sylvia; Harris, Tamara B.; Zeller, Tanja; Zemunik, Tatijana; Lehtimäki, Terho; Illig, Thomas; Aspelund, Thor; Nikopensius, Tiit; Esko, Tonu; Tanaka, Toshiko; Gyllensten, Ulf; Völker, Uwe; Emilsson, Valur; Vitart, Veronique; Aalto, Ville; Gudnason, Vilmundur; Chouraki, Vincent; Chen, Wei-Min; Igl, Wilmar; März, Winfried; Koenig, Wolfgang; Lieb, Wolfgang; Loos, Ruth J. F.; Liu, Yongmei; Snieder, Harold; Pramstaller, Peter P.; Parsa, Afshin; O'Connell, Jeffrey R.; Susztak, Katalin; Hamet, Pavel; Tremblay, Johanne; de Boer, Ian H.; Böger, Carsten A.; Goessling, Wolfram; Chasman, Daniel I.; Köttgen, Anna; Kao, W. H. Linda; Fox, Caroline S. (2016-01)
    Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular ...
  • Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial 

    Keene, Keith L.; Chen, Wei-Min; Chen, Fang; Williams, Stephen R.; Elkhatib, Stacey D.; Hsu, Fang-Chi; Mychaleckyj, Josyf C.; Doheny, Kimberly F.; Pugh, Elizabeth W.; Ling, Hua; Laurie, Cathy C.; Gogarten, Stephanie M.; Madden, Ebony B.; Worrall, Bradford B.; Sale, Michele M. (2014-08)
    Background: B vitamins play an important role in homocysteine metabolism, with vitamin deficiencies resulting in increased levels of homocysteine and increased risk for stroke. We performed a genome-wide association study ...
  • The Genetic Basis of Pigmentation Variation in Domesticated Zebra Finches 

    Pathak,Shaivya (2014)
    The zebra finch is the most common estrildid finch native to Australia and Southeast Asia. The zebra finch has also been domesticated and is now a common pet and experimental model system for research. As part of the ...