Browsing Biology by Title
Now showing items 673-692 of 1310
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Interaction and Functional Analysis of Drosophila Mcm10
(East Carolina University, 2010)In eukaryotic cells, DNA replication and the subsequent packaging of DNA into specific chromatin states are essential processes for the transmission of genetic material and genomic stability which may be linked by interactions ... -
INTERACTION BETWEEN HTLV-1 BASIC LEUCINE ZIPPER FACTOR (HBZ) AND HOST CELL PROTEINS PROMOTES CELLULAR TRANSFORMATION
(2016-04-26)Human T-cell Leukemia Virus Type 1 (HTLV-1) is a complex retrovirus which preferentially infects CD4+ T-cells. Endemic to Japan, regions of South America, Africa, and the Caribbean, HTLV-1 is transmitted through breastfeeding, ... -
Interannual Winter Site Fidelity for Yellow and Black Rails
(2022-05-01) -
Intron position in RNA polymerase genes and their relationship to eukaryotic phylogenies
(East Carolina University, 2010)Over the past two decades, there has been an increasing amount of research devoted to the study of intron evolution and its relationship to eukaryotic phylogeny. Previous studies have shown that a large percentage of ... -
Investigating candidate genes for an association with skin color pattern in the mimic poison frog Ranitomeya imitator
(East Carolina University, 8/5/2020)Understanding the genetic basis of adaptive traits can help us better understand their evolution. The mimic poison frog, Ranitomeya imitator, is native to Peru. Like many other species of poison frogs, it has aposematic ... -
Investigating Genetic Variants of the Folate One Carbon Metabolism (FOCM) Pathway for Associations with Recurrent Stroke and Measures of Homocysteine
(East Carolina University, 2017-07-17)Stroke is currently the fifth leading cause of death and the leading cause of long-term disability in the United States. Stroke accounts for over 140,000 deaths annually and according to the Centers for Disease Control and ... -
Investigating Novel Chromosome 2 Genetic Variants Associated with Recurrent Stroke
(East Carolina University, 2019-07-18)As the fifth leading cause of death and leading cause of long-term disability, stroke affects 795,000 individuals annually in the United States alone. Recurrent stroke, which is far more deadly and disabling, accounts for ... -
INVESTIGATING THE EFFECTS OF LARVAL PHENOTYPES ON TRAITS EXHIBITED AT A CRUCIAL LIFE-HISTORY SWITCH POINT
(East Carolina University, 2017-07-25)In organisms with complex life histories, phenotypes exhibited in non-reproductive life stages are often correlated with adult performance and fitness. For example, in anurans (frogs and toads), age and size at metamorphosis ... -
Investigating the genetic interaction between DNA replication proteins Mcm10 and RecQ4 in Drosophila melanogaster
(East Carolina University, 2017-12-12)Necessary to the survival of cellular life is proper replication and maintenance of the genome. Replication proteins Mcm10 and RecQ4 have well-characterized essential roles in assembly, initiation, proper functioning of ... -
Investigating the Impact of Mettl16 Cellular Localization on RNA Binding Preferences
(East Carolina University, 2019-05-14)Recently, mRNA modification by N6-methyladenosine (m6A) has been shown to be involved in post-transcriptional regulation processes including mRNA stability, splicing and promotion of translation. Accordingly, the mRNA ...