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A Candidate Gene Study: Finding Associations between Recurrent Stroke and Genetic Variants of Five Folate-Mediated One Carbon Metabolism Pathway Genes
(East Carolina University, 2019-04-25)
Stroke is the second leading cause of death in the world and fifth in the United States. Both in the United States and worldwide, stroke is the leading cause of disability. Stroke is a cerebrovascular event which results ...
TEMPERATURE, RESOURCE INPUT, AND STANDING GENETIC VARIATION AFFECT PREDATOR RESPONSES OF PHYSA ACUTA
(East Carolina University, 2019-04-26)
In urban areas, features such as high percentages of impervious ground cover, patchiness, and storm water runoff can lead to increases in temperature and external nutrient input into aquatic systems. Such factors can lead ...
The CDF-type metal efflux protein EmfA is essential for Brucella abortus 2308 resistance to manganese toxicity and is a critical virulence determinant in experimentally-infected mice
(East Carolina University, 2019-05-13)
Divalent cationic metals are important trace nutrients for all bacteria because metals serve as cofactors for proteins involved in numerous cellular functions. Despite the fact that metals play an essential role in bacterial ...
Hickory Shad (Alosa mediocris) Population Identification Using Geometric Morphometrics and Otolith Shape
(East Carolina University, 2019-08-05)
Hickory Shad Alosa mediocris is an anadromous species of fish belonging to the Family Clupeidae, first described in 1814 by Samuel L. Mitchill. Little is known about its life history or stock status. It is unknown whether ...
A metabolomics approach to understanding recurrent stroke risk in African Americans
(East Carolina University, 2019-07-02)
Stroke is a significant health burden, as the fifth leading cause of death and the number one cause of serious, long term disability in the United States. Each year 795,000 individuals suffer a stroke; of which 185,000 ...
Investigating Novel Chromosome 2 Genetic Variants Associated with Recurrent Stroke
(East Carolina University, 2019-07-18)
As the fifth leading cause of death and leading cause of long-term disability, stroke affects 795,000 individuals annually in the United States alone. Recurrent stroke, which is far more deadly and disabling, accounts for ...
Fine-mapping a novel locus on Chromosome 1 for associations with recurrent stroke
(East Carolina University, 2019-07-18)
INTRODUCTION: Stroke is a complex, multifactorial cerebrovascular disease that afflicts millions of individuals both nationally and globally. Of the annual 795,000 stroke incidents, approximately 185,000 are recurrent ...
NATIVE PLANT LANDSCAPING FOR POLLINATORS ON EASTERN NORTH CAROLINA SOLAR FARMS
(East Carolina University, 2019-07-15)
Solar panel farms (SPFs) may be a part of a sustainable solution to pollinator decline and the loss of ecosystem services they provide. Some SPFs are seeking to landscape with diverse native seed mixes, which has the ...
NR5A family member ftz-f1 is necessary to promote oocyte development
(East Carolina University, 2019-07-15)
Gamete production in mammals and insects is intimately tied to nutrition status. Conversion of nutritionally-dependent physiological signals to molecular mechanisms underlying control of oogenesis, however, remains largely ...
Cloning and Characterization of the Classical Maize Mutant, Polytypic1
(East Carolina University, 2019-07-15)
Polytypic1 (Pt1) is a semi-dominant mutant in maize that affects inflorescence development. To understand how Pt1 functions in development, I examined the phenotype of Pt1 mutants in multiple inbred backgrounds. Pt1 defects ...