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Now showing items 271-280 of 503
INVESTIGATING THE EFFECTS OF LARVAL PHENOTYPES ON TRAITS EXHIBITED AT A CRUCIAL LIFE-HISTORY SWITCH POINT
(East Carolina University, 2017-07-25)
In organisms with complex life histories, phenotypes exhibited in non-reproductive life stages are often correlated with adult performance and fitness. For example, in anurans (frogs and toads), age and size at metamorphosis ...
Behavioral and genetic divergence among wild and domesticated populations of the zebra finch (Taeniopygia guttata)
(East Carolina University, 2017-07-18)
Zebra finches (Taeniopygia guttata) have been the subject of extensive neurological and behavioral research having served as the dominant model for vocal learning over half a century. Learned vocal communication, or vocal ...
Characterization of the Bone Marrow Microenvironment During the Development of Triple Negative Breast Cancer Metastases
(East Carolina University, 2017-05-05)
Triple negative breast cancer (TNBC) is a subtype that lacks expression of progesterone and estrogen receptors, and does not over-express human epidermal growth factor receptor 2 (HER2). TNBC is not responsive to standard ...
Characterizing Interactions of Thioflavin-T with Native Proteins Especially Bovine Serum Albumin
(East Carolina University, 2017-05-03)
Thioflavin T is a fluorescent probe used to monitor formation of cross [beta]-sheet rich amyloid fibrils. Involvement of the amyloid fibrils is implicated in more than 50 human diseases, such as Alzheimer's, Parkinson's ...
Impact of Vessel Noise on Oyster Toadfish (Opsanus tau) Behavior and Implications for Underwater Noise Management
(East Carolina University, 2017-05-03)
Underwater noise and its impacts on marine life are growing management concerns. This dissertation considers both the ecological and social concerns of underwater noise, using the oyster toadfish (Opsanus tau) as a model ...
The Effect of Visual Queues on Social Status Formation and Mauthner Sensitivity in Zebrafish
(East Carolina University, 2017-04-27)
Zebrafish of the TLN strain, a genetic variant of the Tüpfel Long-fin (TL) wild-type zebrafish that does not display the trademark striped scale pattern of wild-type zebrafish, but are instead pale, were tested through a ...
HUMAN T-CELL LEUKEMIA VIRUS TYPE 1-ENCODED PROTEIN HBZ INCREASES VIRAL INFECTION
(East Carolina University, 2017-05-04)
Human T-lymphotropic virus type 1 (HTLV-1) is a complex retrovirus, infecting CD4+ T lymphocytes. About 10 million people worldwide are infected with HTLV-1. HTLV-1 has been linked to adult T-cell leukemia (ATL), a disease ...
The Role of Pre-Replication Complex Proteins in Drosophila Ovarian Stem Cell Maintenance and Proliferation
(East Carolina University, 2017-05-05)
Cancer stem cells (CSCs) may hold the key to advances in cancer research. Like adult tissue-specific stem cells, CSCs are able to self-renew and last a lifetime. These shared characteristics can thus be used to help learn ...
INVESTIGATING THE MOLECULAR CONTROL OF ECDYSONE RESPONSE GENE, E74, IN THE DROSOPHILA OVARY.
(East Carolina University, 2017-05-05)
Oogenesis is the process by which an egg develops from precursor cells in the ovary. This process has been widely studied; however, many of the molecular mechanisms that regulate oocyte development and growth remain unclear. ...
Investigating Genetic Variants of the Folate One Carbon Metabolism (FOCM) Pathway for Associations with Recurrent Stroke and Measures of Homocysteine
(East Carolina University, 2017-07-17)
Stroke is currently the fifth leading cause of death and the leading cause of long-term disability in the United States. Stroke accounts for over 140,000 deaths annually and according to the Centers for Disease Control and ...